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UNC13B Antikörper

UNC13B Reaktivität: Human, Maus, Ratte ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7245965
  • Target Alle UNC13B Antikörper anzeigen
    UNC13B (Unc-13 Homolog B (UNC13B))
    Reaktivität
    Human, Maus, Ratte
    Wirt
    • 40
    • 3
    • 1
    Kaninchen
    Klonalität
    • 42
    • 2
    Polyklonal
    Konjugat
    • 20
    • 4
    • 4
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser UNC13B Antikörper ist unkonjugiert
    Applikation
    • 33
    • 25
    • 5
    • 5
    • 2
    • 2
    • 2
    • 2
    • 1
    ELISA, Immunohistochemistry (IHC)
    Produktmerkmale
    Polyclonal Antibody
    Aufreinigung
    Antigen affinity purification
    Immunogen
    Fusion protein of human UNC13B
    Isotyp
    IgG
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  • Applikationshinweise
    IHC 1:30-1:150, ELISA 1:5000-1:10000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    0.6 mg/mL
    Buffer
    PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    UNC13B (Unc-13 Homolog B (UNC13B))
    Andere Bezeichnung
    UNC13B (UNC13B Produkte)
    Synonyme
    MUNC13 antikoerper, UNC13 antikoerper, Unc13h2 antikoerper, UNC13B antikoerper, Munc13-2 antikoerper, Munc13-1 antikoerper, Unc13a antikoerper, Unc13h1 antikoerper, unc-13 homolog B antikoerper, unc-13 homolog B (C. elegans) antikoerper, UNC13B antikoerper, Unc13b antikoerper
    Hintergrund
    This gene is expressed in the kidney cortical epithelial cells and is upregulated by hyperglycemia. The encoded protein shares a high level of similarity to the rat homolog, and contains 3 C2 domains and a diacylglycerol-binding C1 domain. Hyperglycemia increases the levels of diacylglycerol, which has been shown to induce apoptosis in cells transfected with this gene and thus contribute to the renal cell complications of hyperglycemia. Studies in other species also indicate a role for this protein in the priming step of synaptic vesicle exocytosis.
    UniProt
    O14795
    Pathways
    Skeletal Muscle Fiber Development, Synaptic Vesicle Exocytosis
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