SMPD3 Antikörper (N-Term)

Produktnummer ABIN5532184

Produktdetails anti-SMPD3 Antikörper

Target: SMPD3 (Sphingomyelin Phosphodiesterase 3 (SMPD3))

Bindungsspezifität: AA 137-165, N-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SMPD3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This SMPD3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 137-165 amino acids from the N-terminal region of human SMPD3.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: For WB starting dilution is: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu SMPD3

Target: SMPD3 (Sphingomyelin Phosphodiesterase 3 (SMPD3))

Andere Bezeichnung: SMPD3 (SMPD3 Produkte)

Synonyme: 4631433G07Rik antikoerper, AI427456 antikoerper, AW537966 antikoerper, fro antikoerper, nSMase2 antikoerper, cca1 antikoerper, NSMASE2 antikoerper, sphingomyelin phosphodiesterase 3 antikoerper, sphingomyelin phosphodiesterase 3, neutral antikoerper, SMPD3 antikoerper, Smpd3 antikoerper

Hintergrund: SMPD3 catalyzes the hydrolysis of sphingomyelin to form ceramide and phosphocholine. Ceramide mediates numerous cellular functions, such as apoptosis and growth arrest, and is capable of regulating these 2 cellular events independently. Also hydrolyzes sphingosylphosphocholine. Regulates the cell cycle by acting as a growth suppressor in confluent cells. Probably acts as a regulator of postnatal development and participates in bone and dentin mineralization.

Molekulargewicht: 71 kDa

Gen-ID: 55512

UniProt: Q9NY59

Pathways: Hormone Transport