This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This PLEKHF1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 51-79 amino acids from the N-terminal region of human PLEKHF1.
PLEKHF1
Reaktivität: Human
WB, ELISA
Wirt: Kaninchen
Polyclonal
Biotin
Applikationshinweise
For WB starting dilution is: 1:1000
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Konzentration
0.5 mg/mL
Buffer
Supplied in PBS with 0.09 % (W/V) sodium azide.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
4 °C,-20 °C
Informationen zur Lagerung
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Target
PLEKHF1
(Pleckstrin Homology Domain Containing, Family F (With FYVE Domain) Member 1 (PLEKHF1))
zgc:63897 antikoerper, PLEKHF1 antikoerper, APPD antikoerper, LAPF antikoerper, PHAFIN1 antikoerper, ZFYVE15 antikoerper, 1810013P09Rik antikoerper, pleckstrin homology domain containing, family F (with FYVE domain) member 1 antikoerper, pleckstrin homology and FYVE domain containing 1 antikoerper, plekhf1 antikoerper, PLEKHF1 antikoerper, Plekhf1 antikoerper
Hintergrund
PLEKHF1 may induce apoptosis through the lysosomal-mitochondrial pathway. Translocates to the lysosome initiating the permeabilization of lysosomal membrane (LMP) and resulting in the release of CTSD and CTSL to the cytoplasm. Triggers the caspase-independent apoptosis by altering mitochondrial membrane permeabilization (MMP) resulting in the release of PDCD8.