zgc:63897 antikoerper, PLEKHF1 antikoerper, APPD antikoerper, LAPF antikoerper, PHAFIN1 antikoerper, ZFYVE15 antikoerper, 1810013P09Rik antikoerper, pleckstrin homology domain containing, family F (with FYVE domain) member 1 antikoerper, pleckstrin homology and FYVE domain containing 1 antikoerper, plekhf1 antikoerper, PLEKHF1 antikoerper, Plekhf1 antikoerper
Hintergrund
Synonyms:Apoptosis inducing protein, APPD, LAPF, Phafin 1, PHAFIN1, PLEKHF1, ZFYVE15 Background:May induce apoptosis through the lysosomal-mitochondrial pathway. Translocates to the lysosome initiating the permeabilization of lysosomal membrane(LMP) and resulting in the release of CTSD and CTSL to the cytoplasm. Triggers the caspase-independent apoptosis by altering mitochondrial membrane permeabilization(MMP) resulting in the release of PDCD8.