PLEKHF1 Antikörper (AA 75-124)

Produktnummer ABIN872648

Produktdetails anti-PLEKHF1 Antikörper

Target: PLEKHF1 (Pleckstrin Homology Domain Containing, Family F (With FYVE Domain) Member 1 (PLEKHF1))

Bindungsspezifität: AA 75-124

Reaktivität: Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PLEKHF1 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Kreuzreaktivität: Maus, Ratte

Homologie: Human,Dog,Cow,Sheep,Pig,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human APPD/ Apoptosis-inducing protein

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu PLEKHF1

Target: PLEKHF1 (Pleckstrin Homology Domain Containing, Family F (With FYVE Domain) Member 1 (PLEKHF1))

Andere Bezeichnung: APPD (PLEKHF1 Produkte)

Synonyme: zgc:63897 antikoerper, PLEKHF1 antikoerper, APPD antikoerper, LAPF antikoerper, PHAFIN1 antikoerper, ZFYVE15 antikoerper, 1810013P09Rik antikoerper, pleckstrin homology domain containing, family F (with FYVE domain) member 1 antikoerper, pleckstrin homology and FYVE domain containing 1 antikoerper, plekhf1 antikoerper, PLEKHF1 antikoerper, Plekhf1 antikoerper

Hintergrund:

Synonyms: APPD, LAPF, PHAFIN1, ZFYVE15, Pleckstrin homology domain-containing family F member 1, PH domain-containing family F member 1, Lysosome-associated apoptosis-inducing protein containing PH and FYVE domains, Apoptosis-inducing protein, PH and FYVE domain-containing protein 1, Phafin-1, Zinc finger FYVE domain-containing protein 15, PLEKHF1

Background: May induce apoptosis through the lysosomal-mitochondrial pathway. Translocates to the lysosome initiating the permeabilization of lysosomal membrane (LMP) and resulting in the release of CTSD and CTSL to the cytoplasm. Triggers the caspase-independent apoptosis by altering mitochondrial membrane permeabilization (MMP) resulting in the release of PDCD8.

Gen-ID: 79156

UniProt: Q96S99