IL3RA Antikörper (C-Term)

Produktnummer ABIN5517096

Produktdetails anti-IL3RA Antikörper

Target: IL3RA (Interleukin 3 Receptor, alpha (IL3RA))

Bindungsspezifität: C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IL3RA Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: CRRYLVMQRL FPRIPHMKDP IGDSFQNDKL VVWEAGKAGL EECLVTEVQV

Produktmerkmale: This is a rabbit polyclonal antibody against IL3RA. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human IL3RA

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu IL3RA

Target: IL3RA (Interleukin 3 Receptor, alpha (IL3RA))

Andere Bezeichnung: IL3RA (IL3RA Produkte)

Synonyme: CD123 antikoerper, IL3R antikoerper, IL3RAY antikoerper, IL3RX antikoerper, IL3RY antikoerper, hIL-3Ra antikoerper, CDw123 antikoerper, SUT-1 antikoerper, Cyrl antikoerper, interleukin 3 receptor subunit alpha antikoerper, interleukin 3 receptor, alpha chain antikoerper, IL3RA antikoerper, Il3ra antikoerper

Hintergrund: The protein encoded by this gene is an interleukin 3 specific subunit of a heterodimeric cytokine receptor. The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3 (IL3), colony stimulating factor 2 (CSF2/GM-CSF), and interleukin 5 (IL5). The binding of this protein to IL3 depends on the beta subunit. The beta subunit is activated by the ligand binding, and is required for the biological activities of IL3. This gene and the gene encoding the colony stimulating factor 2 receptor alpha chain (CSF2RA) form a cytokine receptor gene cluster in a X-Y pseudoautosomal region on chromosomes X or Y. Alternatively spliced transcript variants encoding distinct isoforms have been found.

Alias Symbols: IL3RA, IL3R,

Protein Interaction Partner: LNX1, FOXP1, SGK2, SAE1, NR0B2, GNA12, CDC25A, CDK1, PPP1CC, JAK1, IL3, CSF2RB, CSF2, CISH, JAK2,

Protein Size: 378

Gen-ID: 3563

NCBI Accession: XP_005274837

UniProt: P26951

Pathways: JAK-STAT Signalweg