GSTa2 Antikörper (N-Term)

Produktnummer ABIN5516878

Produktdetails anti-GSTa2 Antikörper

Target: GSTa2 (Glutathione S-Transferase alpha 2 (GSTa2))

Bindungsspezifität: N-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GSTa2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: KLHYSNIRGR MESIRWLLAA AGVEFEEKFI KSAEDLDKLR NDGYLMFQQV

Aufreinigung: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human GSTA2

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu GSTa2

Target: GSTa2 (Glutathione S-Transferase alpha 2 (GSTa2))

Andere Bezeichnung: GSTA2 (GSTa2 Produkte)

Synonyme: GSTA1 antikoerper, GST2 antikoerper, GSTA2-2 antikoerper, GTA2 antikoerper, GTH2 antikoerper, Gsta1 antikoerper, Gst2-2 antikoerper, Gstc-2 antikoerper, Gstc2 antikoerper, glutathione S-transferase alpha 2 antikoerper, glutathione S-transferase antikoerper, glutathione S-transferase, alpha 2 (Yc2) antikoerper, GSTA2 antikoerper, Gsta2 antikoerper

Hintergrund: Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. These enzymes function in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding these enzymes are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of some drugs. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-tranferase belonging to the alpha class. The alpha class genes, located in a cluster mapped to chromosome 6, are the most abundantly expressed glutathione S-transferases in liver. In addition to metabolizing bilirubin and certain anti-cancer drugs in the liver, the alpha class of these enzymes exhibit glutathione peroxidase activity thereby protecting the cells from reactive oxygen species and the products of peroxidation.

Alias Symbols: GST2, GTA2, GTH2, GSTA2-2,

Protein Size: 222

Gen-ID: 2939

NCBI Accession: NM_000846, NP_000837

UniProt: P09210