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GSTa2 Produkte

(Glutathione S-Transferase alpha 2 (GSTa2))

Kategorien

Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. These enzymes function in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding these enzymes are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of some drugs. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-tranferase belonging to the alpha class. The alpha class genes, located in a cluster mapped to chromosome 6, are the most abundantly expressed glutathione S-transferases in liver. In addition to metabolizing bilirubin and certain anti-cancer drugs in the liver, the alpha class of these enzymes exhibit glutathione peroxidase activity thereby protecting the cells from reactive oxygen species and the products of peroxidation. [provided by RefSeq, Jul 2008].

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Ausgewählte GSTa2 Kategorien

GSTa2 Antikörper

High quality antibodies with extensive validation data.

GSTa2 ELISA Kits

Reliable ELISA kits for a wide range of species.

GSTa2 Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene GSTa2 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation WB, IHC, IP, ICC
Validierungen
  • (6)
Kat. Nr. ABIN7434407
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, ELISA, IF
Validierungen
  • (5)
Kat. Nr. ABIN516223
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, IHC (p)
Validierungen
  • (2)
  • (3)
Kat. Nr. ABIN653362
Menge 400 μL
Datenblatt Datenblatt

Empfohlene GSTa2 ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Rat
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6967114
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6956215
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Cow
Analytical Method
Validierungen
Kat. Nr. ABIN1135014
Menge 96 tests
Datenblatt Datenblatt

Empfohlene GSTa2 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1306063
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1306061
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
  • (1)
Kat. Nr. ABIN3081180
Menge 1 mg
Datenblatt Datenblatt

Neueste Publikationen zu unseren GSTa2 Produkten

Morita, Maeda, Suzuki, Kiyose, Taniguchi, Liu, Sugiyama, Adachi, Kamikubo: "Paradoxical enhancement of leukemogenesis in acute myeloid leukemia with moderately attenuated RUNX1 expressions." in: Blood advances, Vol. 1, Issue 18, pp. 1440-1451, (2018) (PubMed).

Huang, Guo, Li, Zhang: "Activation of Wnt/β-catenin signalling via GSK3 inhibitors direct differentiation of human adipose stem cells into functional hepatocytes." in: Scientific reports, Vol. 7, pp. 40716, (2018) (PubMed).

Venkataraman, den Braver, Vermeulen, Commandeur: "Cytochrome P450-mediated bioactivation of mefenamic acid to quinoneimine intermediates and inactivation by human glutathione S-transferases." in: Chemical research in toxicology, Vol. 27, Issue 12, pp. 2071-81, (2014) (PubMed).

Li, Yuan, Li, Liu, Hua, Lu, Zhang: "Direct differentiation of homogeneous human adipose stem cells into functional hepatocytes by mimicking liver embryogenesis." in: Journal of cellular physiology, Vol. 229, Issue 6, pp. 801-12, (2014) (PubMed).

Synonyme und alternative Namen zu GSTa2

glutathione S-transferase alpha 2 (GSTA2), glutathione S-transferase alpha 2 (Gsta2), glutathione S-transferase (GSTA2), glutathione S-transferase, alpha 2 (Yc2) (Gsta2), GST2, Gst2-2, GSTA1, Gsta1, GSTA2-2, Gstc-2, Gstc2, GTA2, GTH2

Bezeichner auf Proteinebene für GSTa2

  • GST class-alpha member 1
  • GST class-alpha member 2
  • glutathione S-transferase A1
  • glutathione S-transferase A2
  • glutathione S-transferase alpha 1
  • glutathione S-transferase alpha-1
  • glutathione S-transferase alpha-2
  • GST HA subunit 2
  • GST-gamma
  • S-(hydroxyalkyl)glutathione lyase A2
  • glutathione S-alkyltransferase A2
  • glutathione S-aralkyltransferase A2
  • glutathione S-aryltransferase A2
  • liver GST2
  • GST 1-1
  • GST 1a-1a
  • GST A1-1
  • GST B
  • GST Ya1
  • Glutathione-S-transferase alpha type (Yc?)
  • glutathione S-transferase Ya subunit
  • glutathione S-transferase Ya-1
  • glutathione-S-transferase, alpha type2
  • ligandin
  • glutathione S-transferase alpha class A2
  • glutathione S-transferase GT41A
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