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PABPN1 Antikörper (C-Term)
PABPN1
Reaktivität: Human
WB
Wirt: Kaninchen
Polyclonal
unconjugated
Produktnummer ABIN5515697
Produktdetails anti-PABPN1 Antikörper
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Target
Alle PABPN1 Antikörper anzeigen
PABPN1
(Poly A Binding Protein Nuclear 1 (PABPN1))
Bindungsspezifität
Alle Epitope für PABPN1 Antikörper
C-Term
Reaktivität
Alle Reaktivitäten für PABPN1 Antikörper
Human
Wirt
Alle Wirte für PABPN1 Antikörper
Kaninchen
Klonalität
Alle Klonalitäten für PABPN1 Antikörper
Polyklonal
Konjugat
Alle Konjugate für PABPN1 Antikörper
Dieser PABPN1 Antikörper ist unkonjugiert
Applikation
Alle Applikationen für PABPN1 Antikörper
Western Blotting (WB)
Sequenz
NRPGISTTDR GFPRARYRAR TTNYNSSRSR FYSGFNSRPR GRVYRGRARA
Aufreinigung
Affinity purified
Immunogen
The immunogen is a synthetic peptide directed towards the C terminal region of human PABPN1
Top Product
Discover our top product PABPN1 Primärantikörper
Alternativen
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Anwendungsinformationen
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Applikationshinweise
Optimal working dilution should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
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Format
Liquid
Buffer
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 16 % sucrose.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
-20 °C
Informationen zur Lagerung
For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Details zu PABPN1
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Target
PABPN1
(Poly A Binding Protein Nuclear 1 (PABPN1))
Andere Bezeichnung
PABPN1 (PABPN1 Produkte )
Synonyme
OPMD antikoerper, PAB2 antikoerper, PABII antikoerper, PABP-2 antikoerper, PABP2 antikoerper, Pabp3 antikoerper, mPABII antikoerper, ARABIDOPSIS POLY(A) BINDING 2 antikoerper, ATPAB2 antikoerper, F28A23.130 antikoerper, F28A23_130 antikoerper, POLY(A) BINDING PROTEIN 2 antikoerper, POLY(A)-BINDING PROTEIN 2 antikoerper, poly(A) binding protein 2 antikoerper, opmd antikoerper, pab2 antikoerper, pabp2 antikoerper, pabpii antikoerper, pabpn1 antikoerper, Pabpn1 antikoerper, Poly(A)-binding protein 2 antikoerper, fb19c03 antikoerper, wu:fb17e03 antikoerper, wu:fb18c06 antikoerper, wu:fb19c03 antikoerper, zgc:85979 antikoerper, zgc:92452 antikoerper, poly(A) binding protein nuclear 1 antikoerper, poly(A) binding protein, nuclear 1 antikoerper, poly(A) binding protein 2 antikoerper, poly(A) binding protein, nuclear 1 S homeolog antikoerper, poly(A) binding protein, nuclear 1 L homeolog antikoerper, polyadenylate-binding protein 2 antikoerper, poly(A) binding protein Pab2 antikoerper, PABPN1 antikoerper, Pabpn1 antikoerper, PAB2 antikoerper, pabpn1.S antikoerper, pabpn1.L antikoerper, LOC100728725 antikoerper, pab2 antikoerper, pabpn1 antikoerper
Hintergrund
This gene encodes an abundant nuclear protein that binds with high affinity to nascent poly(A) tails. The protein is required for progressive and efficient polymerization of poly(A) tails at the 3' ends of eukaryotic transcripts and controls the size of the poly(A) tail to about 250 nt. At steady-state, this protein is localized in the nucleus whereas a different poly(A) binding protein is localized in the cytoplasm. This gene contains a GCG trinucleotide repeat at the 5' end of the coding region, and expansion of this repeat from the normal 6 copies to 8-13 copies leads to autosomal dominant oculopharyngeal muscular dystrophy (OPMD) disease. Related pseudogenes have been identified on chromosomes 19 and X. Read-through transcription also exists between this gene and the neighboring upstream BCL2-like 2 (BCL2L2) gene. Alias Symbols: OPMD, PAB2, PABII, PABP2, PABP-2, Protein Size: 333
Gen-ID
8106
NCBI Accession
NM_001199839 , NP_004634
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