Rekombinanter PABPN1 Antikörper

Produktnummer ABIN7127661

Produktdetails anti-PABPN1 Antikörper

Target: PABPN1 (Poly A Binding Protein Nuclear 1 (PABPN1))

Antikörpertyp: Recombinant Antibody

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser PABPN1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (IHC), Flow Cytometry (FACS)

Kreuzreaktivität: Human

Aufreinigung: Affinity-chromatography

Immunogen: A synthesized peptide derived from human PABPN1

Klon: 6C3

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: WB:1:500-1:5000, IHC:1:50-1:200, IF:1:20-1:200, FC:1:20-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu PABPN1

Target: PABPN1 (Poly A Binding Protein Nuclear 1 (PABPN1))

Andere Bezeichnung: PABPN1 (PABPN1 Produkte)

Synonyme: OPMD antikoerper, PAB2 antikoerper, PABII antikoerper, PABP-2 antikoerper, PABP2 antikoerper, Pabp3 antikoerper, mPABII antikoerper, ARABIDOPSIS POLY(A) BINDING 2 antikoerper, ATPAB2 antikoerper, F28A23.130 antikoerper, F28A23_130 antikoerper, POLY(A) BINDING PROTEIN 2 antikoerper, POLY(A)-BINDING PROTEIN 2 antikoerper, poly(A) binding protein 2 antikoerper, opmd antikoerper, pab2 antikoerper, pabp2 antikoerper, pabpii antikoerper, pabpn1 antikoerper, Pabpn1 antikoerper, Poly(A)-binding protein 2 antikoerper, fb19c03 antikoerper, wu:fb17e03 antikoerper, wu:fb18c06 antikoerper, wu:fb19c03 antikoerper, zgc:85979 antikoerper, zgc:92452 antikoerper, poly(A) binding protein nuclear 1 antikoerper, poly(A) binding protein, nuclear 1 antikoerper, poly(A) binding protein 2 antikoerper, poly(A) binding protein, nuclear 1 S homeolog antikoerper, poly(A) binding protein, nuclear 1 L homeolog antikoerper, polyadenylate-binding protein 2 antikoerper, poly(A) binding protein Pab2 antikoerper, PABPN1 antikoerper, Pabpn1 antikoerper, PAB2 antikoerper, pabpn1.S antikoerper, pabpn1.L antikoerper, LOC100728725 antikoerper, pab2 antikoerper, pabpn1 antikoerper

Hintergrund:

Background: Involved in the 3'-end formation of mRNA precursors (pre-mRNA) by the addition of a poly(A) tail of 200-250 nt to the upstream cleavage product (By similarity). Stimulates poly(A) polymerase (PAPOLA) conferring processivity on the poly(A) tail elongation reaction and controls also the poly(A) tail length (By similarity). Increases the affinity of poly(A) polymerase for RNA (By similarity). Is also present at various stages of mRNA metabolism including nucleocytoplasmic trafficking and nonsense-mediated decay (NMD) of mRNA. Cooperates with SKIP to synergistically activate E-box-mediated transcription through MYOD1 and may regulate the expression of muscle-specific genes (PubMed:11371506). Binds to poly(A) and to poly(G) with high affinity (By similarity). May protect the poly(A) tail from degradation (By similarity).

Aliases: Polyadenylate-binding protein 2 (PABP-2) (Poly(A)-binding protein 2) (Nuclear poly(A)-binding protein 1) (Poly(A)-binding protein II) (PABII) (Polyadenylate-binding nuclear protein 1), PABPN1, PAB2 PABP2

UniProt: Q86U42