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GNB3 Antikörper (C-Term)
GNB3
Reaktivität: Human
WB
Wirt: Kaninchen
Polyclonal
unconjugated
Produktnummer ABIN5515493
Produktdetails anti-GNB3 Antikörper
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Target
Alle GNB3 Antikörper anzeigen
GNB3
(Guanine Nucleotide Binding Protein (G Protein), beta Polypeptide 3 (GNB3))
Bindungsspezifität
Alle Epitope für GNB3 Antikörper
C-Term
Reaktivität
Alle Reaktivitäten für GNB3 Antikörper
Human
Wirt
Alle Wirte für GNB3 Antikörper
Kaninchen
Klonalität
Alle Klonalitäten für GNB3 Antikörper
Polyklonal
Konjugat
Alle Konjugate für GNB3 Antikörper
Dieser GNB3 Antikörper ist unkonjugiert
Applikation
Alle Applikationen für GNB3 Antikörper
Western Blotting (WB)
Sequenz
SIICGITSVA FSLSGRLLFA GYDDFNCNVW DSMKSERVGI LSGHDNRVSC
Produktmerkmale
This is a rabbit polyclonal antibody against GNB3. It was validated on Western Blot.
Aufreinigung
Affinity Purified
Immunogen
The immunogen is a synthetic peptide directed towards the C-terminal region of Human GNB3
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Discover our top product GNB3 Primärantikörper
Alternativen
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Anwendungsinformationen
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Applikationshinweise
Optimal working dilution should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
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Format
Liquid
Buffer
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
-20 °C
Informationen zur Lagerung
For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Details zu GNB3
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Target
GNB3
(Guanine Nucleotide Binding Protein (G Protein), beta Polypeptide 3 (GNB3))
Andere Bezeichnung
GNB3 (GNB3 Produkte )
Synonyme
Gnb-3 antikoerper, MGC68913 antikoerper, MGC130764 antikoerper, gnb3 antikoerper, zgc:73058 antikoerper, zgc:77780 antikoerper, wu:fk54b04 antikoerper, gnb3l antikoerper, zgc:92641 antikoerper, G protein subunit beta 3 antikoerper, guanine nucleotide binding protein (G protein), beta 3 antikoerper, guanine nucleotide binding protein (G protein), beta polypeptide 3 S homeolog antikoerper, guanine nucleotide binding protein (G protein), beta polypeptide 3b antikoerper, guanine nucleotide binding protein (G protein), beta polypeptide 3a antikoerper, GNB3 antikoerper, Gnb3 antikoerper, gnb3.S antikoerper, gnb3b antikoerper, gnb3a antikoerper
Hintergrund
Heterotrimeric guanine nucleotide-binding proteins (G proteins), which integrate signals between receptors and effector proteins, are composed of an alpha, a beta, and a gamma subunit. These subunits are encoded by families of related genes. This gene encodes a beta subunit. Beta subunits are important regulators of alpha subunits, as well as of certain signal transduction receptors and effectors. A single-nucleotide polymorphism (C825T) in this gene is associated with essential hypertension and obesity. This polymorphism is also associated with the occurrence of the splice variant GNB3-s, which appears to have increased activity. GNB3-s is an example of alternative splicing caused by a nucleotide change outside of the splice donor and acceptor sites. Additional splice variants may exist for this gene, but they have not been fully described. Alias Symbols: GNB3, Protein Interaction Partner: UBC, MTOR, GNG8, GNG12, GNG2, GNG10, GNG5, GNAQ, GNAI3, GNA12, RASD2, PDCL, GNG13, RGS6, GNGT2, GNG11, GNG7, GNG4, GNG3, TGFBR1, git11, Protein Size: 340
Gen-ID
2784
NCBI Accession
NP_002066
UniProt
P16520
Pathways
Peptide Hormone Metabolism , Myometrial Relaxation and Contraction
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