GNB3 Antikörper (AA 81-180)

Produktnummer ABIN751498

Produktdetails anti-GNB3 Antikörper

Target: GNB3 (Guanine Nucleotide Binding Protein (G Protein), beta Polypeptide 3 (GNB3))

Bindungsspezifität: AA 81-180

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GNB3 Antikörper ist unkonjugiert

Applikation: ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Homologie: Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human G protein beta 3

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu GNB3

Target: GNB3 (Guanine Nucleotide Binding Protein (G Protein), beta Polypeptide 3 (GNB3))

Andere Bezeichnung: G protein beta 3/GNB3 (GNB3 Produkte)

Synonyme: Gnb-3 antikoerper, MGC68913 antikoerper, MGC130764 antikoerper, gnb3 antikoerper, zgc:73058 antikoerper, zgc:77780 antikoerper, wu:fk54b04 antikoerper, gnb3l antikoerper, zgc:92641 antikoerper, G protein subunit beta 3 antikoerper, guanine nucleotide binding protein (G protein), beta 3 antikoerper, guanine nucleotide binding protein (G protein), beta polypeptide 3 S homeolog antikoerper, guanine nucleotide binding protein (G protein), beta polypeptide 3b antikoerper, guanine nucleotide binding protein (G protein), beta polypeptide 3a antikoerper, GNB3 antikoerper, Gnb3 antikoerper, gnb3.S antikoerper, gnb3b antikoerper, gnb3a antikoerper

Hintergrund:

Synonyms: Gnb3, Guanine nucleotide binding protein G protein, beta polypeptide 3, Guanine nucleotide binding protein G, Hypertension associated protein, IG, SG, Transducin beta chain 3, Tsubunit beta 3, GBB3_HUMAN.

Background: G proteins are composed of 3 units, alpha, beta and gamma and are involved in the modulation and transduction of various transmembrane signalling systems. There are families of related genes for each subunit. GNB3 encodes a beta subunit. Beta subunits are required for GTPase activity, for replacement of GDP by GTP, regulate alpha subunits and for G protein-effector interactions. A single-nucleotide polymorphism (C825T) in this gene is associated with essential hypertension and obesity and is also associated with the occurrence of the splice variant GNB3-s, which appears to have increased activity.

Gen-ID: 2784

Pathways: Peptide Hormone Metabolism, Myometrial Relaxation and Contraction