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UNC13B Antikörper (Middle Region)
UNC13B
Reaktivität: Human
WB
Wirt: Kaninchen
Polyclonal
unconjugated
Produktnummer ABIN5515349
Produktdetails anti-UNC13B Antikörper
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Target
Alle UNC13B Antikörper anzeigen
UNC13B
(Unc-13 Homolog B (UNC13B))
Bindungsspezifität
Alle Epitope für UNC13B Antikörper
Middle Region
Reaktivität
Alle Reaktivitäten für UNC13B Antikörper
Human
Wirt
Alle Wirte für UNC13B Antikörper
Kaninchen
Klonalität
Alle Klonalitäten für UNC13B Antikörper
Polyklonal
Konjugat
Alle Konjugate für UNC13B Antikörper
Dieser UNC13B Antikörper ist unkonjugiert
Applikation
Alle Applikationen für UNC13B Antikörper
Western Blotting (WB)
Sequenz
SYDLDYPERR AISPTSSSRY GSSCNVSQGS SQLSELDQYH EQDDDHRETD
Aufreinigung
Affinity purified
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of human UNC13B
Top Product
Discover our top product UNC13B Primärantikörper
Alternativen
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Anwendungsinformationen
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Applikationshinweise
Optimal working dilution should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
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Format
Liquid
Buffer
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
-20 °C
Informationen zur Lagerung
For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Details zu UNC13B
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Target
UNC13B
(Unc-13 Homolog B (UNC13B))
Andere Bezeichnung
UNC13B (UNC13B Produkte )
Synonyme
MUNC13 antikoerper, UNC13 antikoerper, Unc13h2 antikoerper, UNC13B antikoerper, Munc13-2 antikoerper, Munc13-1 antikoerper, Unc13a antikoerper, Unc13h1 antikoerper, unc-13 homolog B antikoerper, unc-13 homolog B (C. elegans) antikoerper, UNC13B antikoerper, Unc13b antikoerper
Hintergrund
This gene is expressed in the kidney cortical epithelial cells and is upregulated by hyperglycemia. The encoded protein shares a high level of similarity to the rat homolog, and contains 3 C2 domains and a diacylglycerol-binding C1 domain. Hyperglycemia increases the levels of diacylglycerol, which has been shown to induce apoptosis in cells transfected with this gene and thus contribute to the renal cell complications of hyperglycemia. Studies in other species also indicate a role for this protein in the priming step of synaptic vesicle exocytosis. Alias Symbols: UNC13, MUNC13, Unc13h2 Protein Size: 1591
Gen-ID
10497
NCBI Accession
NM_006377 , NP_006368
UniProt
O14795
Pathways
Skeletal Muscle Fiber Development , Synaptic Vesicle Exocytosis
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