PCGF2 Antikörper (Middle Region)

Produktnummer ABIN5514708

Produktdetails anti-PCGF2 Antikörper

Target: PCGF2 (Polycomb Group Ring Finger 2 (PCGF2))

Bindungsspezifität: Middle Region

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PCGF2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: EQEKGALSDD EIVSLSIEFY EGARDRDEKK GPLENGDGDK EKTGVRFLRC

Aufreinigung: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human PCGF2

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 16 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu PCGF2

Target: PCGF2 (Polycomb Group Ring Finger 2 (PCGF2))

Andere Bezeichnung: PCGF2 (PCGF2 Produkte)

Synonyme: ZNF144 antikoerper, PCGF2 antikoerper, MEL-18 antikoerper, RNF110 antikoerper, Mel18 antikoerper, Rnf110 antikoerper, Zfp144 antikoerper, mel-18 antikoerper, polycomb group ring finger 2 antikoerper, PCGF2 antikoerper, Pcgf2 antikoerper

Hintergrund: The protein encoded by this gene contains a RING finger motif and is similar to the polycomb group (PcG) gene products. PcG gene products form complexes via protein-protein interaction and maintain the transcription repression of genes involved in embryogenesis, cell cycles, and tumorigenesis. This protein was shown to act as a negative regulator of transcription and has tumor suppressor activity. The expression of this gene was detected in various tumor cells, but is limited in neural organs in normal tissues. Knockout studies in mice suggested that this protein may negatively regulate the expression of different cytokines, chemokines, and chemokine receptors, and thus plays an important role in lymphocyte differentiation and migration, as well as in immune responses.

Alias Symbols: MEL-18, RNF110, ZNF144,

Protein Size: 344

Gen-ID: 7703

NCBI Accession: NM_007144, NP_009075

UniProt: P35227

Pathways: Chromatin Binding