PCGF2 Antikörper

Produktnummer ABIN7269450

Produktdetails anti-PCGF2 Antikörper

Target: PCGF2 (Polycomb Group Ring Finger 2 (PCGF2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PCGF2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Verwendungszweck: PCGF2 Rabbit pAb

Kreuzreaktivität: Human, Ratte

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant protein of human PCGF2.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu PCGF2

Target: PCGF2 (Polycomb Group Ring Finger 2 (PCGF2))

Andere Bezeichnung: PCGF2 (PCGF2 Produkte)

Synonyme: ZNF144 antikoerper, PCGF2 antikoerper, MEL-18 antikoerper, RNF110 antikoerper, Mel18 antikoerper, Rnf110 antikoerper, Zfp144 antikoerper, mel-18 antikoerper, polycomb group ring finger 2 antikoerper, PCGF2 antikoerper, Pcgf2 antikoerper

Hintergrund: The protein encoded by this gene contains a RING finger motif and is similar to the polycomb group (PcG) gene products. PcG gene products form complexes via protein-protein interaction and maintain the transcription repression of genes involved in embryogenesis, cell cycles, and tumorigenesis. This protein was shown to act as a negative regulator of transcription and has tumor suppressor activity. The expression of this gene was detected in various tumor cells, but is limited in neural organs in normal tissues. Knockout studies in mice suggested that this protein may negatively regulate the expression of different cytokines, chemokines, and chemokine receptors, and thus plays an important role in lymphocyte differentiation and migration, as well as in immune responses.,PCGF2,MEL-18,RNF110,ZNF144,Epigenetics & Nuclear Signaling,Chromatin Remodeling,Cancer,Tumor suppressors,Cell Biology & Developmental Biology,Ubiquitin,Stem Cells,Hematopoietic Progenitors,PCGF2

Molekulargewicht: 38kDa

Gen-ID: 7703

UniProt: P35227

Pathways: Chromatin Binding