×
Aktivieren Sie Javascript in Ihrem Browser, um unsere Webseite optimal zu nutzen.
DFFA Antikörper (Middle Region)
DFFA
Reaktivität: Human
WB
Wirt: Kaninchen
Polyclonal
unconjugated
Produktnummer ABIN5514702
Produktdetails anti-DFFA Antikörper
(ausblenden)
Target
Alle DFFA Antikörper anzeigen
DFFA
(DNA Fragmentation Factor, 45kDa, alpha Polypeptide (DFFA))
Bindungsspezifität
Alle Epitope für DFFA Antikörper
Middle Region
Reaktivität
Alle Reaktivitäten für DFFA Antikörper
Human
Wirt
Alle Wirte für DFFA Antikörper
Kaninchen
Klonalität
Alle Klonalitäten für DFFA Antikörper
Polyklonal
Konjugat
Alle Konjugate für DFFA Antikörper
Dieser DFFA Antikörper ist unkonjugiert
Applikation
Alle Applikationen für DFFA Antikörper
Western Blotting (WB)
Sequenz
DYFLCLPSNT KFVALASNEK WAYNNSDGGT AWISQESFDV DETDSGAGLK
Aufreinigung
Affinity purified
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of human DFFA
Top Product
Discover our top product DFFA Primärantikörper
Alternativen
(anzeigen)
Anwendungsinformationen
(ausblenden)
Applikationshinweise
Optimal working dilution should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
(ausblenden)
Format
Liquid
Buffer
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
-20 °C
Informationen zur Lagerung
For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Details zu DFFA
(ausblenden)
Target
DFFA
(DNA Fragmentation Factor, 45kDa, alpha Polypeptide (DFFA))
Andere Bezeichnung
DFFA (DFFA Produkte )
Synonyme
DFF-45 antikoerper, DFF1 antikoerper, ICAD antikoerper, A330085O09Rik antikoerper, DFF35 antikoerper, Dff45 antikoerper, ICAD-L antikoerper, ICAD-S antikoerper, DFFA antikoerper, zgc:92229 antikoerper, DNA fragmentation factor subunit alpha antikoerper, DNA fragmentation factor, alpha subunit antikoerper, DNA fragmentation factor, 45kDa, alpha polypeptide antikoerper, DNA fragmentation factor, alpha polypeptide antikoerper, DFFA antikoerper, Dffa antikoerper, dffa antikoerper
Hintergrund
Apoptosis is a cell death process that removes toxic and/or useless cells during mammalian development. The apoptotic process is accompanied by shrinkage and fragmentation of the cells and nuclei and degradation of the chromosomal DNA into nucleosomal units. DNA fragmentation factor (DFF) is a heterodimeric protein of 40-kD (DFFB) and 45-kD (DFFA) subunits. DFFA is the substrate for caspase-3 and triggers DNA fragmentation during apoptosis. DFF becomes activated when DFFA is cleaved by caspase-3. The cleaved fragments of DFFA dissociate from DFFB, the active component of DFF. DFFB has been found to trigger both DNA fragmentation and chromatin condensation during apoptosis. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. Alias Symbols: DFF1, ICAD, DFF-45, Protein Size: 167
Gen-ID
1676
NCBI Accession
NM_004401 , NP_004392
UniProt
O00273
Pathways
Apoptose , Caspase Kaskade in der Apoptose
Zuletzt angesehen
(ausblenden)