Western Blot (1 μg/mL) Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1 μg/mL) The optimal working dilution should be determined by the end user.
This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
Lagerung
-20 °C
Informationen zur Lagerung
Store at -20°C on dry atmosphere. After reconstitution with 200 uL of deionized water and concentration will be 500 ug/mL, store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Bierhaus, Haslbeck, Humpert, Liliensiek, Dehmer, Morcos, Sayed, Andrassy, Schiekofer, Schneider, Schulz, Heuss, Neundörfer, Dierl, Huber, Tritschler, Schmidt, Schwaninger, Haering, Schleicher, Kasper et al.: "Loss of pain perception in diabetes is dependent on a receptor of the immunoglobulin superfamily. ..." in: The Journal of clinical investigation, Vol. 114, Issue 12, pp. 1741-51, (2004) (PubMed).
Chavakis, Bierhaus, Al-Fakhri, Schneider, Witte, Linn, Nagashima, Morser, Arnold, Preissner, Nawroth: "The pattern recognition receptor (RAGE) is a counterreceptor for leukocyte integrins: a novel pathway for inflammatory cell recruitment." in: The Journal of experimental medicine, Vol. 198, Issue 10, pp. 1507-15, (2003) (PubMed).
Taguchi, Blood, del Toro, Canet, Lee, Qu, Tanji, Lu, Lalla, Fu, Hofmann, Kislinger, Ingram, Lu, Tanaka, Hori, Ogawa, Stern, Schmidt: "Blockade of RAGE-amphoterin signalling suppresses tumour growth and metastases." in: Nature, Vol. 405, Issue 6784, pp. 354-60, (2000) (PubMed).
Target
RAGE (AGER)
(Advanced Glycosylation End Product-Specific Receptor (AGER))