RAGE Antikörper (AA 76-104)
Kurzübersicht für RAGE Antikörper (AA 76-104) (ABIN3029883)
Target
Alle RAGE (AGER) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
-
-
Bindungsspezifität
- AA 76-104
-
Verwendungszweck
- Rage Antibody
-
Aufreinigung
- Antigen affinity
-
Immunogen
- A portion of amino acids 76-104 from the mouse protein was used as the immunogen for this Rage antibody.
-
Isotyp
- Ig Fraction
-
-
-
-
Applikationshinweise
- Titration of the Rage antibody may be required due to differences in protocols and secondary/substrate sensitivity.
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Liquid
-
Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
-
Konservierungsmittel
- Sodium azide
-
Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Lagerung
- -20 °C
-
Informationen zur Lagerung
- Aliquot the Rage antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
-
-
- RAGE (AGER) (Advanced Glycosylation End Product-Specific Receptor (AGER))
-
Andere Bezeichnung
- Rage
-
Hintergrund
- RAGE, the 'receptor for advanced glycation endproducts' is a transmembrane receptor of the immunoglobulin super family. The interaction between RAGE and its ligands, AGE and HMGB1, is thought to result in pro-inflammatory gene activation. Due to an enhanced level of RAGE ligands in diabetes or other chronic disorders, this receptor is hypothesised to have a causative effect in a range of inflammatory diseases such as diabetic complications, Alzheimer's disease and even some tumors. [Wiki]
-
UniProt
- Q9WVS4
-
Pathways
- Carbohydrate Homeostasis, Toll-Like Receptors Cascades, Smooth Muscle Cell Migration, S100 Proteine
Target
-