LYN Antikörper (N-Term)

Produktnummer ABIN544389

Produktdetails anti-LYN Antikörper

Target: LYN (V-Yes-1 Yamaguchi Sarcoma Viral Related Oncogene Homolog (LYN))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser LYN Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Verwendungszweck: Rabbit polyclonal antibody raised against synthetic peptide of LYN.

Kreuzreaktivität: Human, Maus

Immunogen: A synthetic peptide (conjugated with KLH) corresponding to N-terminus of human LYN.

Anwendungsinformationen

Applikationshinweise: Flow Cytometry (1:10-50)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:50-100)
Western Blot (1:1000)
The optimal working dilution should be determined by the end user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: In PBS (0.09 % sodium azide)

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.

Referenzen für anti-LYN Antikörper (ABIN544389)

Baran, Tridandapani, Helgason, Humphries, Krystal, Marsh: "The inositol 5'-phosphatase SHIP-1 and the Src kinase Lyn negatively regulate macrophage colony-stimulating factor-induced Akt activity." in: The Journal of biological chemistry, Vol. 278, Issue 40, pp. 38628-36, (2003) (PubMed).

Donato, Wu, Stapley, Gallick, Lin, Arlinghaus, Talpaz: "BCR-ABL independence and LYN kinase overexpression in chronic myelogenous leukemia cells selected for resistance to STI571." in: Blood, Vol. 101, Issue 2, pp. 690-8, (2003) (PubMed).

Santini, Scappini, Grossi, Gozzini, Bonsi, Pagliai, Rossi Ferrini, Bagnara: "Lyn kinase is activated following thrombopoietin stimulation of the megakaryocytic cell line B1647." in: Haematologica, Vol. 87, Issue 12, pp. 1242-7, (2002) (PubMed).

Details zu LYN

Target: LYN (V-Yes-1 Yamaguchi Sarcoma Viral Related Oncogene Homolog (LYN))

Andere Bezeichnung: LYN (LYN Produkte)

Synonyme: JTK8 antikoerper, p53Lyn antikoerper, p56Lyn antikoerper, lyn antikoerper, LYN antikoerper, AA407514 antikoerper, Hck-2 antikoerper, jtk8 antikoerper, lyn-A antikoerper, CH73-38P6.3 antikoerper, zgc:92124 antikoerper, LYN proto-oncogene, Src family tyrosine kinase antikoerper, v-yes-1 Yamaguchi sarcoma viral related oncogene homolog antikoerper, tyrosine-protein kinase Lyn antikoerper, LYN proto-oncogene, Src family tyrosine kinase L homeolog antikoerper, LYN antikoerper, lyn antikoerper, Lyn antikoerper, LOC100593961 antikoerper, lyn.L antikoerper

Gen-ID: 4067

Pathways: Fc-epsilon Rezeptor Signalübertragung, Hormone Transport, Response to Growth Hormone Stimulus, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, CXCR4-mediated Signaling Events, Thromboxane A2 Receptor Signaling, Integrin Complex, BCR Signaling