APEX1 Antikörper

Produktnummer ABIN540784

Produktdetails anti-APEX1 Antikörper

Target: APEX1 (Apurinic/Apyrimidinic Endonuclease 1 (APEX1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser APEX1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro))

Verwendungszweck: Rabbit polyclonal antibody raised against recombinant APEX1.

Spezifität: This antibody is specific to the human APE/ref-1protein.

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Antibody Reactive Against Recombinant Protein.

Immunogen: Recombinant protein corresponding to human APEX1.

Anwendungsinformationen

Applikationshinweise: Immunocytochemistry (1:50-1:200)
Immunofluorescence (1:50-1:200)
Immunoprecipitation (7 μg/mL)
Western Blot (1:1000)
The optimal working dilution should be determined by the end user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: In Tris-glycine, 150 mM NaCl (0.05 % sodium azide)

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Store at -20°C or -80°C.
Aliquot to avoid repeated freezing and thawing.

Referenzen für anti-APEX1 Antikörper (ABIN540784)

Lam, Bussom, Cheng: "Effect of hypoxia on the expression of phosphoglycerate kinase and antitumor activity of troxacitabine and gemcitabine in non-small cell lung carcinoma." in: Molecular cancer therapeutics, Vol. 8, Issue 2, pp. 415-23, (2009) (PubMed).

Yang, Chen, Zhang, Huang, Zhang: "Virion-associated uracil DNA glycosylase-2 and apurinic/apyrimidinic endonuclease are involved in the degradation of APOBEC3G-edited nascent HIV-1 DNA." in: The Journal of biological chemistry, Vol. 282, Issue 16, pp. 11667-75, (2007) (PubMed).

Raffoul, Banerjee, Singh-Gupta, Knoll, Fite, Zhang, Abrams, Sarkar, Hillman: "Down-regulation of apurinic/apyrimidinic endonuclease 1/redox factor-1 expression by soy isoflavones enhances prostate cancer radiotherapy in vitro and in vivo." in: Cancer research, Vol. 67, Issue 5, pp. 2141-9, (2007) (PubMed).

Briegert, Kaina: "Human monocytes, but not dendritic cells derived from them, are defective in base excision repair and hypersensitive to methylating agents." in: Cancer research, Vol. 67, Issue 1, pp. 26-31, (2007) (PubMed).

Yang, DeBusk, Fukuda, Fingleton, Green-Jarvis, Shyr, Matrisian, Carbone, Lin: "Expansion of myeloid immune suppressor Gr+CD11b+ cells in tumor-bearing host directly promotes tumor angiogenesis." in: Cancer cell, Vol. 6, Issue 4, pp. 409-21, (2004) (PubMed).

Details zu APEX1

Target: APEX1 (Apurinic/Apyrimidinic Endonuclease 1 (APEX1))

Andere Bezeichnung: APEX1 / REF-1 (APEX1 Produkte)

Synonyme: apex1 antikoerper, MGC76280 antikoerper, MGC79645 antikoerper, MGC78928 antikoerper, APE antikoerper, APE1 antikoerper, APEN antikoerper, APEX antikoerper, APX antikoerper, HAP1 antikoerper, REF1 antikoerper, Apex antikoerper, REF-1 antikoerper, BAP1 antikoerper, apex1a antikoerper, hm:zehn1532 antikoerper, wu:fc13d11 antikoerper, zgc:66204 antikoerper, Ref-1 antikoerper, apurinic/apyrimidinic endodeoxyribonuclease 1 antikoerper, APEX nuclease (multifunctional DNA repair enzyme) 1 antikoerper, APEX nuclease (multifunctional DNA repair enzyme) 1 L homeolog antikoerper, DNA-(apurinic or apyrimidinic site) lyase antikoerper, apurinic/apyrimidinic endonuclease 1 antikoerper, APEX1 antikoerper, apex1 antikoerper, apex1.L antikoerper, CNG03640 antikoerper, CNH01280 antikoerper, nth antikoerper, Spirs_4119 antikoerper, Palpr_0103 antikoerper, Apex1 antikoerper

Gen-ID: 328

Pathways: DNA Reparatur, Chromatin Binding, Cell RedoxHomeostasis, Smooth Muscle Cell Migration, Positive Regulation of Response to DNA Damage Stimulus