p130 Antikörper

Produktnummer ABIN539487

Produktdetails anti-p130 Antikörper

Target: p130 (RBL2) (Retinoblastoma-Like 2 (p130) (RBL2))

Reaktivität: Human, Schimpanse, Orang-Utan

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser p130 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunoprecipitation (IP)

Verwendungszweck: Rabbit polyclonal antibody raised against synthetic peptide of RBL2.

Spezifität: This antiserum is directed against Spa310 and reacts with the Spa3120 domain of pRb2/p130 from human tissues.

Kreuzreaktivität: Schimpanse, Human, Orang-Utan

Produktmerkmale: Antibody Reactive Against Synthetic Peptide.

Immunogen: A synthetic peptide corresponding to the Spa310 domain of human RBL2.

Anwendungsinformationen

Applikationshinweise: ELISA (1:75000-1:100000)
Western Blot (1:500-1:5000)
The optimal working dilution should be determined by the end user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: In 20 mM KH₂PO₄, 150 mM NaCl, pH 7.2 (0.09 % sodium azide)

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.

Referenzen für anti-p130 Antikörper (ABIN539487)

Bagella, Sun, Tonini, Abbadessa, Cottone, Paggi, De Luca, Claudio, Giordano: "A small molecule based on the pRb2/p130 spacer domain leads to inhibition of cdk2 activity, cell cycle arrest and tumor growth reduction in vivo." in: Oncogene, Vol. 26, Issue 13, pp. 1829-39, (2007) (PubMed).

Sun, Bagella, Tutton, Romano, Giordano: "From G0 to S phase: a view of the roles played by the retinoblastoma (Rb) family members in the Rb-E2F pathway." in: Journal of cellular biochemistry, Vol. 102, Issue 6, pp. 1400-4, (2007) (PubMed).

DAndrilli, Masciullo, Bagella, Tonini, Minimo, Zannoni, Giuntoli, Carlson, Soprano, Soprano, Scambia, Giordano: "Frequent loss of pRb2/p130 in human ovarian carcinoma." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 10, Issue 9, pp. 3098-103, (2004) (PubMed).

Details zu p130

Target: p130 (RBL2) (Retinoblastoma-Like 2 (p130) (RBL2))

Andere Bezeichnung: RBL2 / p130 (RBL2 Produkte)

Synonyme: RBL2 antikoerper, RBR2 antikoerper, RRB2a antikoerper, PRB2 antikoerper, RBR-2 antikoerper, Rb2 antikoerper, p130 antikoerper, P130 antikoerper, retinoblastoma-like 2 (p130) antikoerper, RB transcriptional corepressor like 2 antikoerper, related to retinoblastoma 2 antikoerper, RBL2 antikoerper, LOC541652 antikoerper, Rbl2 antikoerper

Gen-ID: 5934

Pathways: Zellzyklus, Mitotic G1-G1/S Phases