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p130 Antikörper

RBL2 Reaktivität: Human, Ratte, Maus ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7247960
  • Target Alle p130 (RBL2) Antikörper anzeigen
    p130 (RBL2) (Retinoblastoma-Like 2 (p130) (RBL2))
    Reaktivität
    • 75
    • 29
    • 27
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    Human, Ratte, Maus
    Wirt
    • 65
    • 10
    Kaninchen
    Klonalität
    • 65
    • 10
    Polyklonal
    Konjugat
    • 34
    • 6
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser p130 Antikörper ist unkonjugiert
    Applikation
    • 37
    • 29
    • 14
    • 13
    • 13
    • 9
    • 7
    • 6
    • 6
    • 3
    • 1
    • 1
    • 1
    • 1
    ELISA, Immunohistochemistry (IHC)
    Produktmerkmale
    Polyclonal Antibody
    Aufreinigung
    Antigen affinity purification
    Immunogen
    Synthetic peptide of human RBL2
    Isotyp
    IgG
    Top Product
    Discover our top product RBL2 Primärantikörper
  • Applikationshinweise
    IHC 1:30-1:150, ELISA 1:5000-1:10000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    0.8 mg/mL
    Buffer
    PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    p130 (RBL2) (Retinoblastoma-Like 2 (p130) (RBL2))
    Andere Bezeichnung
    RBL2 (RBL2 Produkte)
    Synonyme
    RBL2 antikoerper, RBR2 antikoerper, RRB2a antikoerper, PRB2 antikoerper, RBR-2 antikoerper, Rb2 antikoerper, p130 antikoerper, P130 antikoerper, retinoblastoma-like 2 (p130) antikoerper, RB transcriptional corepressor like 2 antikoerper, related to retinoblastoma 2 antikoerper, RBL2 antikoerper, LOC541652 antikoerper, Rbl2 antikoerper
    Hintergrund
    Key regulator of entry into cell division. Directly involved in heterochromatin formation by maintaining overall chromatin structure and, in particular, that of constitutive heterochromatin by stabilizing histone methylation. Recruits and targets histone methyltransferases KMT5B and KMT5C, leading to epigenetic transcriptional repression. Controls histone H4 'Lys-20' trimethylation. Probably acts as a transcription repressor by recruiting chromatin-modifying enzymes to promoters. Potent inhibitor of E2F-mediated trans-activation, associates preferentially with E2F5. Binds to cyclins A and E. Binds to and may be involved in the transforming capacity of the adenovirus E1A protein. May act as a tumor suppressor.
    UniProt
    Q08999
    Pathways
    Zellzyklus, Mitotic G1-G1/S Phases
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