PERK Antikörper (AA 601-1115)

Produktnummer ABIN538307

Produktdetails anti-PERK Antikörper

Target: PERK (EIF2AK3) (Eukaryotic Translation Initiation Factor 2-alpha Kinase 3 (EIF2AK3))

Bindungsspezifität: AA 601-1115

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PERK Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP)

Verwendungszweck: Rabbit polyclonal antibody raised against partial recombinant Eif2ak3.

Kreuzreaktivität: Maus

Produktmerkmale: Antibody Reactive Against Recombinant Protein.

Immunogen: Recombinant protein corresponding to amino acids 601-1115 of mouse Eif2ak3.

Anwendungsinformationen

Applikationshinweise: Western Blot (1:500-1:3000)
Immunoprecipitation (10-30 µL)
The optimal working dilution should be determined by the end user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: In 20 mM KH₂PO₄, 150 mM NaCl, pH 7.2 (0.01 % sodium azide)

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.

Referenzen für anti-PERK Antikörper (ABIN538307)

Lee, Surh: "Nrf2 as a novel molecular target for chemoprevention." in: Cancer letters, Vol. 224, Issue 2, pp. 171-84, (2005) (PubMed).

Cullinan, Zhang, Hannink, Arvisais, Kaufman, Diehl: "Nrf2 is a direct PERK substrate and effector of PERK-dependent cell survival." in: Molecular and cellular biology, Vol. 23, Issue 20, pp. 7198-209, (2003) (PubMed).

Ma, Vattem, Wek: "Dimerization and release of molecular chaperone inhibition facilitate activation of eukaryotic initiation factor-2 kinase in response to endoplasmic reticulum stress." in: The Journal of biological chemistry, Vol. 277, Issue 21, pp. 18728-35, (2002) (PubMed).

Details zu PERK

Target: PERK (EIF2AK3) (Eukaryotic Translation Initiation Factor 2-alpha Kinase 3 (EIF2AK3))

Andere Bezeichnung: EIF2AK3 (EIF2AK3 Produkte)

Synonyme: EIF2AK3 antikoerper, AI427929 antikoerper, Pek antikoerper, Perk antikoerper, PEK antikoerper, PERK antikoerper, WRS antikoerper, eukaryotic translation initiation factor 2 alpha kinase 3 antikoerper, EIF2AK3 antikoerper, Eif2ak3 antikoerper

Gen-ID: 13666

Pathways: Hormone Transport, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Hepatitis C, Unfolded Protein Response