ECT2 Antikörper (pThr790)

Produktnummer ABIN538145

Produktdetails anti-ECT2 Antikörper

Target: ECT2 (Epithelial Cell Transforming Sequence 2 Oncogene (ECT2))

Bindungsspezifität: pThr790

Reaktivität: Human, Maus, Ratte, Hund, Zebrafisch (Danio rerio), Affe, Huhn

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ECT2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Verwendungszweck: Rabbit polyclonal antibody raised against synthetic phosphopeptide of ECT2.

Spezifität: Reactivity occurs against human ECT2 protein at the pT790 residue. By ELISA This antibody is specific to the phosphorylated form of the protein. Reactivity with non-phosphorylated human ECT2 is minimal by ELISA, but western blot shows specific staining of interphase cell lysates, which are predicted to contain non-phosphorylated ECT2.

Kreuzreaktivität: Huhn, Schimpanse, Hund, Human, Maus, Ratte, Zebrafisch (Danio rerio)

Produktmerkmale: Antibody Reactive Against Synthetic Peptide.

Immunogen: Synthetic phosphopeptide corresponding to residues surrounding T790 of human ECT2.

Anwendungsinformationen

Applikationshinweise: ELISA (1:10000-1:40000)
Western Blot (1:1000-1:4000)
The optimal working dilution should be determined by the end user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: In 20 mM KH₂PO₄, 150 mM NaCl, pH 7.2 (0.01 % sodium azide)

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.

Referenzen für anti-ECT2 Antikörper (ABIN538145)

Niiya, Xie, Lee, Inoue, Miki: "Inhibition of cyclin-dependent kinase 1 induces cytokinesis without chromosome segregation in an ECT2 and MgcRacGAP-dependent manner." in: The Journal of biological chemistry, Vol. 280, Issue 43, pp. 36502-9, (2005) (PubMed).

Zhao, Fang: "MgcRacGAP controls the assembly of the contractile ring and the initiation of cytokinesis." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 102, Issue 37, pp. 13158-63, (2005) (PubMed).

Kim, Billadeau, Chen: "The tandem BRCT domains of Ect2 are required for both negative and positive regulation of Ect2 in cytokinesis." in: The Journal of biological chemistry, Vol. 280, Issue 7, pp. 5733-9, (2005) (PubMed).

Details zu ECT2

Target: ECT2 (Epithelial Cell Transforming Sequence 2 Oncogene (ECT2))

Andere Bezeichnung: ECT2 (ECT2 Produkte)

Synonyme: ECT2 antikoerper, arhgef31 antikoerper, xect2 antikoerper, AI528536 antikoerper, mKIAA4037 antikoerper, ARHGEF31 antikoerper, ect2 antikoerper, epithelial cell transforming 2 antikoerper, ect2 oncogene antikoerper, epithelial cell transforming 2 S homeolog antikoerper, ECT2 antikoerper, ect2 antikoerper, Ect2 antikoerper, ect2.S antikoerper

Gen-ID: 1894

Pathways: Neurotrophin Signalübertragung, Cell-Cell Junction Organization