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ECT2 Produkte

(Epithelial Cell Transforming Sequence 2 Oncogene (ECT2))

Kategorien

The protein encoded by this gene is a guanine nucleotide exchange factor and transforming protein that is related to Rho-specific exchange factors and yeast cell cycle regulators. The expression of this gene is elevated with the onset of DNA synthesis and remains elevated during G2 and M phases. In situ hybridization analysis showed that expression is at a high level in cells undergoing mitosis in regenerating liver. Thus, this protein is expressed in a cell cycle-dependent manner during liver regeneration, and is thought to have an important role in the regulation of cytokinesis. Several transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Apr 2012].

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Ausgewählte ECT2 Kategorien

ECT2 Antikörper

High quality antibodies with extensive validation data.

ECT2 Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene ECT2 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation ICC, IHC, WB
Validierungen
  • (4)
Kat. Nr. ABIN1858683
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation ICC, IHC, WB
Validierungen
  • (4)
Kat. Nr. ABIN1175693
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation ELISA, IHC, IP, WB
Validierungen
  • (3)
Kat. Nr. ABIN7165313
Menge 100 μg
Datenblatt Datenblatt

Empfohlene ECT2 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Insect Cells
Validierungen
  • (1)
Kat. Nr. ABIN3092269
Menge 1 mg
Datenblatt Datenblatt
Reaktivität Mouse
Source Insect Cells
Validierungen
  • (1)
Kat. Nr. ABIN3134853
Menge 1 mg
Datenblatt Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN2565141
Menge 10 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren ECT2 Produkten

Wang, Yan, Liu: "Clinical significance of ECT2 expression in tissue and serum of gastric cancer patients." in: Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico, Vol. 18, Issue 7, pp. 735-42, (2016) (PubMed).

Guo, Chen, Du, Zhu, Lai, Dong, Wu, Lin, Liu, Huang: "Elevated levels of epithelial cell transforming sequence 2 predicts poor prognosis for prostate cancer." in: Medical oncology (Northwood, London, England), Vol. 34, Issue 1, pp. 13, (2016) (PubMed).

Niiya, Xie, Lee, Inoue, Miki: "Inhibition of cyclin-dependent kinase 1 induces cytokinesis without chromosome segregation in an ECT2 and MgcRacGAP-dependent manner." in: The Journal of biological chemistry, Vol. 280, Issue 43, pp. 36502-9, (2005) (PubMed).

Zhao, Fang: "MgcRacGAP controls the assembly of the contractile ring and the initiation of cytokinesis." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 102, Issue 37, pp. 13158-63, (2005) (PubMed).

Kim, Billadeau, Chen: "The tandem BRCT domains of Ect2 are required for both negative and positive regulation of Ect2 in cytokinesis." in: The Journal of biological chemistry, Vol. 280, Issue 7, pp. 5733-9, (2005) (PubMed).

Tatsumoto, Xie, Blumenthal, Okamoto, Miki: "Human ECT2 is an exchange factor for Rho GTPases, phosphorylated in G2/M phases, and involved in cytokinesis." in: The Journal of cell biology, Vol. 147, Issue 5, pp. 921-8, (1999) (PubMed).

Synonyme und alternative Namen zu ECT2

epithelial cell transforming 2 (ECT2), epithelial cell transforming 2 (ect2), ect2 oncogene (Ect2), epithelial cell transforming 2 S homeolog (ect2.S), epithelial cell transforming 2 (Ect2), AI528536, arhgef31, ARHGEF31, ECT2, ect2, mKIAA4037, xect2

Bezeichner auf Proteinebene für ECT2

  • epithelial cell transforming sequence 2 oncogene
  • protein ECT2-like
  • epithelial cell-transforming sequence 2 oncogene
  • protein ECT2
  • epithelial cell transforming sequence 2 oncogene protein
  • ect2 oncogene
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