EDG4 Produkte
(Lysophosphatidic Acid Receptor 2 (LPAR2))
Kategorien
This gene encodes a member of family I of the G protein-coupled receptors, as well as the EDG family of proteins. This protein functions as a lysophosphatidic acid (LPA) receptor and contributes to Ca2+ mobilization, a critical cellular response to LPA in cells, through association with Gi and Gq proteins. An alternative splice variant has been described but its full length sequence has not been determined. [provided by RefSeq, Jul 2008].
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Ausgewählte EDG4 Kategorien
EDG4 Antikörper
High quality antibodies with extensive validation data.
EDG4 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene EDG4 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, IHC (p)
Validierungen
- (5)
- (3)
Kat. Nr.
ABIN390085
Menge
400 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
IHC (p), ICC
Validierungen
- (3)
Kat. Nr.
ABIN1910280
Menge
50 μg
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, IHC (p)
Validierungen
- (1)
- (2)
Kat. Nr.
ABIN545645
Menge
400 μL
Datenblatt
Datenblatt
Empfohlene EDG4 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1309684
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Insect Cells
Validierungen
- (1)
Kat. Nr.
ABIN3118260
Menge
1 mg
Datenblatt
Datenblatt
Reaktivität
Mouse
Source
Insect Cells
Validierungen
- (1)
Kat. Nr.
ABIN3130274
Menge
1 mg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren EDG4 Produkten
: "Evaluation of pancreatic cancer cell migration with multiple parameters in vitro by using an optical real-time cell mobility assay device." in: BMC cancer, Vol. 17, Issue 1, pp. 234, (2017) (PubMed).: "LPA Induces Colon Cancer Cell Proliferation through a Cooperation between the ROCK and STAT-3 Pathways." in: PLoS ONE, Vol. 10, Issue 9, pp. e0139094, (2015) (PubMed).
: "LPA signaling through LPA receptors regulates cellular functions of endothelial cells treated with anticancer drugs." in: Molecular and cellular biochemistry, Vol. 408, Issue 1-2, pp. 147-54, (2015) (PubMed).
: "In vivo collective cell migration requires an LPAR2-dependent increase in tissue fluidity." in: The Journal of cell biology, Vol. 206, Issue 1, pp. 113-27, (2014) (PubMed).
: "Lysophosphatidic acid increases proximal tubule cell secretion of profibrotic cytokines PDGF-B and CTGF through LPA2- and G?q-mediated Rho and ?v?6 integrin-dependent activation of TGF-?." in: The American journal of pathology, Vol. 181, Issue 4, pp. 1236-49, (2012) (PubMed).
: "Lysophosphatidic acid receptor activation affects the C13NJ microglia cell line proteome leading to alterations in glycolysis, motility, and cytoskeletal architecture." in: Proteomics, Vol. 10, Issue 1, pp. 141-58, (2010) (PubMed).
: "Lysophosphatidic acid induces Ca2+ mobilization and c-Myc expression in mouse embryonic stem cells via the phospholipase C pathway." in: Cellular signalling, Vol. 21, Issue 4, pp. 523-8, (2009) (PubMed).
: "Nm23-H1 suppresses tumor cell motility by down-regulating the lysophosphatidic acid receptor EDG2." in: Cancer research, Vol. 67, Issue 15, pp. 7238-46, (2007) (PubMed).
: "RGS18 acts as a negative regulator of osteoclastogenesis by modulating the acid-sensing OGR1/NFAT signaling pathway." in: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, Vol. 22, Issue 10, pp. 1612-20, (2007) (PubMed).
: "Genome-wide gene expression profiling of human mast cells stimulated by IgE or FcepsilonRI-aggregation reveals a complex network of genes involved in inflammatory responses." in: BMC genomics, Vol. 7, pp. 210, (2006) (PubMed).
Synonyme und alternative Namen zu EDG4
lysophosphatidic acid receptor 2 (LPAR2), lysophosphatidic acid receptor 2 S homeolog (lpar2.S), G protein-coupled bile acid receptor 1 (GPBAR1), lysophosphatidic acid receptor 2 (Lpar2), growth hormone releasing hormone receptor (GHRHR), lysophosphatidic acid receptor 2a (lpar2a), EDG-4, EDG4, Edg4, Gpbar1, IPA2, LPA-2, LPA2, lpa2, Pbx4, RGD1561336, zgc:101053Bezeichner auf Proteinebene für EDG4
- G protein-coupled receptor
- LPA receptor 2
- LPA receptor EDG4
- endothelial differentiation, lysophosphatidic acid G-protein-coupled receptor, 4
- lysophosphatidic acid receptor EDG4
- lysophosphatidic acid receptor Edg-4
- G-protein coupled bile acid receptor 1
- LPA-2
- endothelial differentiation, lysophosphatidic acid G-protein-coupled receptor 4
- GHRF receptor
- GHRH receptor
- GRF receptor
- growth hormone-releasing hormone receptor
- pituitary growth hormone releasing hormone receptor
- pre-B-cell leukemia transcription factor 4
- lysophosphatidic acid receptor 2
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