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CD45 Antikörper

Name: CD45 Antikörper
SKU: ABIN535487
Price: 646.8 EUR
Availability: InStock

PTPRC Reaktivität: Human FACS Wirt: Maus Monoclonal MEM-143 unconjugated

(3 Referenzen)

Produktnummer ABIN535487

Datenblatt (PDF)

Target Alle CD45 (PTPRC) Antikörper anzeigen

CD45 (PTPRC) (Protein tyrosine Phosphatase, Receptor Type, C (PTPRC))
Reaktivität
410

252

88

29

20

16

15

10

7

6

6

6

4

4

3

3

2

1

1

1

1

1

1

1

1

1
Human
Wirt
305

201

139

2

1

1
Maus
Passende Sekundärantikörper
Klonalität
513

128

1
Monoklonal
Konjugat
185

60

52

50

38

17

15

12

12

12

10

10

10

10

8

7

6

6

6

6

5

5

5

4

4

4

4

4

4

4

4

4

4

4

4

3

3

3

3

3

3

3

3

2

2

2

2

2

2

1

1
Dieser CD45 Antikörper ist unkonjugiert
Applikation
527

204

156

137

135

80

61

60

47

27

19

17

15

14

13

7

5

5

5

4

3

3

3

3

3

2

2

2

2

1

1

1

1

1

1

1

1
Flow Cytometry (FACS)

Verwendungszweck

Mouse monoclonal antibody raised against native PTPRC.

Spezifität

This antibody reacts with a protein determinant of CD45RB, a 180-240 KDa singlechain type I membrane glycoprotein, variant of CD45 (CD45RB isoform). CD45RB isexpressed on a subset of T lymphocytes, B lymphocytes, monocytes, macrophages, granulocytes and dendritic cells.The MEM-143 is therefore not neuraminidase sensitive. The reactivity of This antibody can be blocked by a peptide including amino acids 79-88.

Kreuzreaktivität

Human

Immunogen

Native purified PTPRC from human peripheral blood lymphocytes.

Klon

MEM-143

Isotyp

IgG1

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PTPRC Reaktivität: Human FACS, IHC, WB, IF, ELISA Wirt: Maus Monoclonal 17H9D4 unconjugated

anti-Protein tyrosine Phosphatase, Receptor Type, C (PTPRC) (C-Term) antibody
PTPRC Reaktivität: Human, Maus, Ratte, Hund, Huhn, Rind (Kuh), Cat, Kaninchen, Schaf, Schwein, Meerschweinchen, Ziege, Pferd, Affe, Avian, Esel, Hamster WB Wirt: Ziege Polyclonal unconjugated

anti-Protein tyrosine Phosphatase, Receptor Type, C (PTPRC) (AA 378-577) antibody
PTPRC Reaktivität: Human, Maus, Ratte FACS, IHC, WB, ELISA, ICC Wirt: Maus Monoclonal 2H3E2 unconjugated

anti-Protein tyrosine Phosphatase, Receptor Type, C (PTPRC) (AA 431-577) antibody
PTPRC Reaktivität: Human FACS, IHC, WB, ELISA, ICC, Neut Wirt: Maus Monoclonal 7C9F12 unconjugated

anti-Protein tyrosine Phosphatase, Receptor Type, C (PTPRC) (AA 928-989) antibody
PTPRC Reaktivität: Human IHC, WB, ELISA Wirt: Maus Monoclonal 5D3A3 unconjugated

Applikationshinweise

The optimal working dilution should be determined by the end user.

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Buffer

In PBS, pH 7.4 (0.09 % sodium azide)

Konservierungsmittel

Sodium azide

Vorsichtsmaßnahmen

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung

4 °C

Informationen zur Lagerung

Store at 4°C. Do not freeze.
Aliquot to avoid repeated freezing and thawing.
Desharnais, Dupéré-Minier, Hamelin, Devine, Bernier: "Involvement of CD45 in DNA fragmentation in apoptosis induced by mitochondrial perturbing agents." in: Apoptosis : an international journal on programmed cell death, Vol. 13, Issue 2, pp. 197-212, (2008) (PubMed).

Bijian, Zhang, Shen: "Collagen-mediated survival signaling is modulated by CD45 in Jurkat T cells." in: Molecular immunology, Vol. 44, Issue 15, pp. 3682-90, (2007) (PubMed).

Dawes, Petrova, Liu, Wraith, Beverley, Tchilian: "Combinations of CD45 isoforms are crucial for immune function and disease." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 176, Issue 6, pp. 3417-25, (2006) (PubMed).
Target

CD45 (PTPRC) (Protein tyrosine Phosphatase, Receptor Type, C (PTPRC))

Andere Bezeichnung

PTPRC (PTPRC Produkte)

Synonyme

PTPRC antikoerper, si:dkeyp-47c5.1 antikoerper, B220 antikoerper, CD45 antikoerper, CD45R antikoerper, GP180 antikoerper, L-CA antikoerper, LCA antikoerper, LY5 antikoerper, T200 antikoerper, Cd45 antikoerper, Ly-5 antikoerper, Lyt-4 antikoerper, loc antikoerper, Lca antikoerper, RT7 antikoerper, cd45 antikoerper, protein tyrosine phosphatase, receptor type C antikoerper, protein tyrosine phosphatase, receptor type, C antikoerper, receptor-type tyrosine-protein phosphatase C antikoerper, PTPRC antikoerper, ptprc antikoerper, LOC100074271 antikoerper, Ptprc antikoerper

Gen-ID

5788

Pathways

T-Zell Rezeptor Signalweg, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, CXCR4-mediated Signaling Events, BCR Signaling