Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)
Verwendungszweck
Mouse monoclonal antibody raised against partial recombinant FOLH1.
Spezifität
This antibody recognizes amino acids 100-104 of extracellular domain of denaturated glutamate carboxypeptidase II (PSMA, NAALADase, FOLH1), an approximately 95-110 KDa transmembrane glycoprotein.
Kreuzreaktivität
Human, Schwein, Ratte
Immunogen
Recombinant protein corresponding to amino acids 44-750 of human FOLH1.
FOLH1
Reaktivität: Human
WB, ELISA
Wirt: Maus
Monoclonal
3B5
unconjugated
Applikationshinweise
Western Blot (1 μg/mL) The optimal working dilution should be determined by the end user.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Konzentration
1 mg/mL
Buffer
In PBS, pH 7.4 (0.09 % sodium azide)
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
4 °C
Informationen zur Lagerung
Store at 4°C. Do not freeze.
Mukherji, Janbandhu, Kumar: "GSK-3beta-dependent destabilization of cyclin D1 mediates replicational stress-induced arrest of cell cycle." in: FEBS letters, Vol. 582, Issue 7, pp. 1111-6, (2008) (PubMed).
Yang, Zhang, Li, Wu, Zhu: "Myostatin induces cyclin D1 degradation to cause cell cycle arrest through a phosphatidylinositol 3-kinase/AKT/GSK-3 beta pathway and is antagonized by insulin-like growth factor 1." in: The Journal of biological chemistry, Vol. 282, Issue 6, pp. 3799-808, (2007) (PubMed).