PSMA Produkte
(Folate Hydrolase (Prostate-Specific Membrane Antigen) 1 (FOLH1))
Kategorien
This gene encodes a type II transmembrane glycoprotein belonging to the M28 peptidase family. The protein acts as a glutamate carboxypeptidase on different alternative substrates, including the nutrient folate and the neuropeptide N-acetyl-l-aspartyl-l-glutamate and is expressed in a number of tissues such as prostate, central and peripheral nervous system and kidney. A mutation in this gene may be associated with impaired intestinal absorption of dietary folates, resulting in low blood folate levels and consequent hyperhomocysteinemia. Expression of this protein in the brain may be involved in a number of pathological conditions associated with glutamate excitotoxicity. In the prostate the protein is up-regulated in cancerous cells and is used as an effective diagnostic and prognostic indicator of prostate cancer. This gene likely arose from a duplication event of a nearby chromosomal region. Alternative splicing gives rise to multiple transcript variants encoding several different isoforms. [provided by RefSeq, Jul 2010].
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Ausgewählte PSMA Kategorien
PSMA Antikörper
High quality antibodies with extensive validation data.
PSMA ELISA Kits
Reliable ELISA kits for a wide range of species.
PSMA Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene PSMA Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human, Mouse, Pig, Rat
Applikation
WB, IHC (p), ICC
Validierungen
- (9)
- (8)
Kat. Nr.
ABIN1302364
Menge
0.1 mg
Datenblatt
Datenblatt
Reaktivität
Human, Mouse, Rat
Applikation
IHC
Validierungen
- (6)
Kat. Nr.
ABIN7234408
Menge
200 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, IHC, ICC, IP
Validierungen
- (5)
Kat. Nr.
ABIN7443569
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene PSMA ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
- (1)
Kat. Nr.
ABIN6975679
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6962642
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
Kat. Nr.
ABIN6951666
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene PSMA Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
HEK-293 Cells
Validierungen
- (3)
Kat. Nr.
ABIN7275493
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
HEK-293 Cells
Validierungen
- (3)
Kat. Nr.
ABIN7275491
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Cynomolgus
Source
HEK-293 Cells
Validierungen
- (3)
Kat. Nr.
ABIN7275488
Menge
100 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren PSMA Produkten
: "Prostate-Specific Membrane Antigen in Anaplastic and Poorly Differentiated Thyroid Cancer-A New Diagnostic and Therapeutic Target?" in: Cancers, Vol. 13, Issue 22, (2021) (PubMed).: "Prostate specific membrane antigen (PSMA) in urothelial cell carcinoma (UCC) is associated with tumor grading and staging." in: Journal of cancer research and clinical oncology, (2020) (PubMed).
: "Overexpression of prostate specific membrane antigen by canine hemangiosarcoma cells provides opportunity for the molecular detection of disease burdens within hemorrhagic body cavity effusions." in: PLoS ONE, Vol. 14, Issue 1, pp. e0210297, (2019) (PubMed).
: "Heterogeneous PSMA expression on circulating tumor cells: a potential basis for stratification and monitoring of PSMA-directed therapies in prostate cancer." in: Oncotarget, Vol. 7, Issue 23, pp. 34930-41, (2018) (PubMed).
: "Mice lacking glutamate carboxypeptidase II develop normally, but are less susceptible to traumatic brain injury." in: Journal of neurochemistry, Vol. 134, Issue 2, pp. 340-53, (2015) (PubMed).
: "Automated multiplexed ECL Immunoarrays for cancer biomarker proteins." in: Analytical chemistry, Vol. 87, Issue 8, pp. 4472-8, (2015) (PubMed).
: "Comparative analysis of monoclonal antibodies against prostate-specific membrane antigen (PSMA)." in: The Prostate, Vol. 74, Issue 16, pp. 1674-90, (2014) (PubMed).
: "Flexible gold electrode array for multiplexed immunoelectrochemical measurement of three protein biomarkers for prostate cancer." in: ACS applied materials & interfaces, Vol. 6, Issue 22, pp. 20137-43, (2014) (PubMed).
: "Immunohistological and electrophysiological evidence that N-acetylaspartylglutamate is a co-transmitter at the vertebrate neuromuscular junction." in: The European journal of neuroscience, Vol. 37, Issue 1, pp. 118-29, (2013) (PubMed).
: "Multiplex epitope mapping using bacterial surface display reveals both linear and conformational epitopes." in: Scientific reports, Vol. 2, pp. 706, (2012) (PubMed).
Synonyme und alternative Namen zu PSMA
putative N-acetylated-alpha-linked acidic dipeptidase (LOC451185), folate hydrolase 1B (FOLH1B), folate hydrolase 1 (FOLH1), folate hydrolase (prostate-specific membrane antigen) 1 (FOLH1), folate hydrolase 1 (Folh1), FGCP, FOLH, GCP2, GCPII, mGCP, mopsm, Naalad, NAALAD1, NAALAdase, PSM, PSMABezeichner auf Proteinebene für PSMA
- folate hydrolase 1
- glutamate carboxypeptidase 2
- folate hydrolase (prostate-specific membrane antigen) 1
- glutamate carboxypeptidase 2-like
- N-acetylated alpha-linked acidic dipeptidase 1
- N-acetylated-alpha-linked acidic dipeptidase I
- NAALADase I
- cell growth-inhibiting gene 27 protein
- folylpoly-gamma-glutamate carboxypeptidase
- glutamate carboxylase II
- glutamate carboxypeptidase II
- membrane glutamate carboxypeptidase
- prostate specific membrane antigen variant F
- pteroylpoly-gamma-glutamate carboxypeptidase
- FGCP
- GCPII
- mGCP
- prostate-specific membrane antigen homolog
- prostate-specific membrane antigen
- N-acetylated alpha-linked acidic dipeptidase
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