PSMA Antikörper (AA 232-433)

Produktnummer ABIN6939424

Der Maus Monoklonal anti-PSMA Antikörper wird verwendet zum Nachweis von PSMA in Proben von Human, Hund, Pferd und Cat. Er wurde validiert für WB und IHC.

Kurzübersicht für PSMA Antikörper (AA 232-433) (ABIN6939424)

Target: PSMA (FOLH1) (Folate Hydrolase (Prostate-Specific Membrane Antigen) 1 (FOLH1))

Reaktivität: Human, Hund, Pferd, Cat

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser PSMA Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Klon: FOLH1-2354

Produktdetails anti-PSMA Antikörper

Bindungsspezifität: AA 232-433

Verwendungszweck: FOLH1 / PSMA (Prostate Epithelial Marker) Antibody

Spezifität: Folate hydrolase 1 (FOLH1), also known as Prostate-specific membrane antigen (PSMA), is a type II transmembrane glycoprotein belonging to the M28 peptidase family. FOLH1 has two enzymatic activities, one as a prostate-specific integral membrane folate hydrolase and the other as a carboxypeptidase In the prostate the protein is up-regulated in cancerous cells and is used as an effective diagnostic and prognostic indicator of prostate cancer.

Aufreinigung: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Recombinant human FOLH1 protein fragment (around aa 232-433) (exact sequence is proprietary)

Isotyp: IgG2b, kappa

Anwendungsinformationen

Applikationshinweise:

Positive Control: LNCap or HepG2 cells. Prostate Carcinoma.

Known Application: Western Blot (1-2 μg/mL), Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Haltbarkeit: 24 months

Details zu PSMA

Target: PSMA (FOLH1) (Folate Hydrolase (Prostate-Specific Membrane Antigen) 1 (FOLH1))

Andere Bezeichnung: FOLH1

Hintergrund:

Cell growth-inhibiting gene 27 protein (GIG27), Folate hydrolase 1 (FOLH1), Folylpoly-gamma-glutamate carboxypeptidase (FGCP), Glutamate carboxylase II (GCPII), Glutamate carboxypeptidase 2 (GCP2), Glutamate carboxypeptidase II Membrane glutamate carboxypeptidase N-acetylated-alpha-linked acidic dipeptidase I (NAALAD1 or NAALADase), Prostate-specific membrane antigen (PSM or PSMA), Pteroylpoly-gamma-glutamate carboxypeptidase

LNCap or HepG2 cells. Prostate Carcinoma.

Molekulargewicht: 100kDa

Gen-ID: 2346, 654487

UniProt: Q04609