ARNT Antikörper (AA 496-789)

Produktnummer ABIN534093

Produktdetails anti-ARNT Antikörper

Target: ARNT (Aryl Hydrocarbon Receptor Nuclear Translocator (ARNT))

Bindungsspezifität: AA 496-789

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser ARNT Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Verwendungszweck: Mouse monoclonal antibody raised against partial recombinant ARNT.

Spezifität: This antibody is specific to HIF-1 beta /ARNT.

Kreuzreaktivität: Rind (Kuh), Frettchen, Human, Maus, Ratte, Schaf

Produktmerkmale: Antibody Reactive Against Recombinant Protein.

Immunogen: Recombinant protein corresponding to amino acids 496-789 of human ARNT.

Klon: H1beta234

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Western Blot (1:500)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:100)
The optimal working dilution should be determined by the end user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: In PBS (0.05 % sodium azide)

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Store at -20°C or -80°C.
Aliquot to avoid repeated freezing and thawing.

Referenzen für anti-ARNT Antikörper (ABIN534093)

Do, Fink, Jensen, Gautier, Parlesak: "TLR2 controls intestinal carcinogen detoxication by CYP1A1." in: PLoS ONE, Vol. 7, Issue 3, pp. e32309, (2012) (PubMed).

Kransler, McGarrigle, Swartz, Olson: "Lung development in the Holtzman rat is adversely affected by gestational exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin." in: Toxicological sciences : an official journal of the Society of Toxicology, Vol. 107, Issue 2, pp. 498-511, (2009) (PubMed).

Lauzier, Robitaille, Chan, Giaccia, Richard: "(2R)-[(4-Biphenylylsulfonyl)amino]-N-hydroxy-3-phenylpropionamide (BiPS), a matrix metalloprotease inhibitor, is a novel and potent activator of hypoxia-inducible factors." in: Molecular pharmacology, Vol. 74, Issue 1, pp. 282-8, (2008) (PubMed).

Puppo, Battaglia, Ottaviano, Delfino, Ribatti, Varesio, Bosco: "Topotecan inhibits vascular endothelial growth factor production and angiogenic activity induced by hypoxia in human neuroblastoma by targeting hypoxia-inducible factor-1alpha and -2alpha." in: Molecular cancer therapeutics, Vol. 7, Issue 7, pp. 1974-84, (2008) (PubMed).

Aminova, Siddiq, Ratan et al.: "Antioxidants, HIF prolyl hydroxylase inhibitors or short interfering RNAs to BNIP3 or PUMA, can prevent prodeath effects of the transcriptional activator, HIF-1alpha, in a mouse hippocampal neuronal ..." in: Antioxidants & redox signaling, Vol. 10, Issue 12, pp. 1989-98, (2008) (PubMed).

Baek, Liu, McDonald, Wesley, Hubbi, Byun, Semenza: "Spermidine/spermine-N1-acetyltransferase 2 is an essential component of the ubiquitin ligase complex that regulates hypoxia-inducible factor 1alpha." in: The Journal of biological chemistry, Vol. 282, Issue 32, pp. 23572-80, (2007) (PubMed).

Details zu ARNT

Target: ARNT (Aryl Hydrocarbon Receptor Nuclear Translocator (ARNT))

Andere Bezeichnung: HIF1 beta / ARNT (ARNT Produkte)

Synonyme: HIF-1-beta antikoerper, HIF-1beta antikoerper, HIF1-beta antikoerper, HIF1B antikoerper, HIF1BETA antikoerper, TANGO antikoerper, bHLHe2 antikoerper, D3Ertd557e antikoerper, Drnt antikoerper, ESTM42 antikoerper, Hif1b antikoerper, W08714 antikoerper, mKIAA4051 antikoerper, Arnt1 antikoerper, ARNT antikoerper, zgc:136664 antikoerper, arnt1 antikoerper, hif1b antikoerper, tango antikoerper, xArnt antikoerper, hif1beta antikoerper, hif-1beta antikoerper, arnt.2 antikoerper, MGC68805 antikoerper, aryl hydrocarbon receptor nuclear translocator antikoerper, aryl hydrocarbon receptor nuclear translocator S homeolog antikoerper, ARNT antikoerper, Arnt antikoerper, arnt antikoerper, arnt.S antikoerper

Gen-ID: 405

Pathways: Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Regulation of Carbohydrate Metabolic Process, Signaling Events mediated by VEGFR1 and VEGFR2, Warburg Effekt