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ARNT Produkte

(Aryl Hydrocarbon Receptor Nuclear Translocator (ARNT))

Kategorien

The aryl hydrocarbon (Ah) receptor is involved in the induction of several enzymes that participate in xenobiotic metabolism. The ligand-free, cytosolic form of the Ah receptor is complexed to heat shock protein 90. Binding of ligand, which includes dioxin and polycyclic aromatic hydrocarbons, results in translocation of the ligand-binding subunit only to the nucleus. Induction of enzymes involved in xenobiotic metabolism occurs through binding of the ligand-bound Ah receptor to xenobiotic responsive elements in the promoters of genes for these enzymes. This gene encodes a protein that forms a complex with the ligand-bound Ah receptor, and is required for receptor function. The encoded protein has also been identified as the beta subunit of a heterodimeric transcription factor, hypoxia-inducible factor 1. A t(1\;12)(q21\;p13) translocation, which results in a TEL-ARNT fusion protein, is associated with acute myeloblastic leukemia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2010].

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Ausgewählte ARNT Kategorien

ARNT Antikörper

High quality antibodies with extensive validation data.

ARNT ELISA Kits

Reliable ELISA kits for a wide range of species.

ARNT Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene ARNT Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation WB, ELISA, IF, IHC (p), RNAi
Validierungen
  • (7)
Kat. Nr. ABIN559953
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, IF
Validierungen
  • (1)
  • (4)
Kat. Nr. ABIN513506
Menge 50 μg
Datenblatt Datenblatt
Reaktivität Human, Mouse, Rat
Applikation WB, IHC, ELISA, IF, ICC
Validierungen
  • (4)
Kat. Nr. ABIN6260045
Menge 100 μL
Datenblatt Datenblatt

Empfohlene ARNT ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Mouse
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
  • (1)
Kat. Nr. ABIN6953934
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Rat
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6965029
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6953933
Menge 96 tests
Datenblatt Datenblatt

Empfohlene ARNT Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
  • (1)
Kat. Nr. ABIN1345671
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1345673
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Insect Cells
Validierungen
  • (1)
Kat. Nr. ABIN3089209
Menge 1 mg
Datenblatt Datenblatt

Neueste Publikationen zu unseren ARNT Produkten

Rahman, Thomas: "Molecular cloning and characterization of two ARNT (ARNT-1 and ARNT-2) genes in Atlantic croaker and their expression during coexposure to hypoxia and PCB77." in: Environmental toxicology, Vol. 34, Issue 2, pp. 160-171, (2019) (PubMed).

Smythies, Sun, Masson, Salama, Simpson, Murray, Neumann, Cockman, Choudhry, Ratcliffe, Mole: "Inherent DNA-binding specificities of the HIF-1α and HIF-2α transcription factors in chromatin." in: EMBO reports, Vol. 20, Issue 1, (2019) (PubMed).

Louphrasitthiphol, Ledaki, Chauhan, Falletta, Siddaway, Buffa, Mole, Soga, Goding: "MITF controls the TCA cycle to modulate the melanoma hypoxia response." in: Pigment cell & melanoma research, (2019) (PubMed).

Samanta, Park, Ni, Li, Zahnow, Gabrielson, Pan, Semenza: "Chemotherapy induces enrichment of CD47+/CD73+/PDL1+ immune evasive triple-negative breast cancer cells." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 115, Issue 6, pp. E1239-E1248, (2018) (PubMed).

Kim, Seok, Byun, Kong, Zhang, Guo, Xie, Ma, Kemper, Kemper: "AhR and SHP regulate phosphatidylcholine and S-adenosylmethionine levels in the one-carbon cycle." in: Nature communications, Vol. 9, Issue 1, pp. 540, (2018) (PubMed).

Rodrigues, Patel, Harewood, Olan, Vojtasova, Syafruddin, Zaini, Richardson, Burge, Warren, Stewart, Saeb-Parsy, Samarajiwa, Vanharanta: "NF-κB-Dependent Lymphoid Enhancer Co-option Promotes Renal Carcinoma Metastasis." in: Cancer discovery, Vol. 8, Issue 7, pp. 850-865, (2018) (PubMed).

Wang, Yuan, Wang, Yang, Chen, Liu, Song, Feng, Tan, Jia: "Anti-inflammatory Effects of Phyllanthus emblica L on Benzopyrene-Induced Precancerous Lung Lesion by Regulating the IL-1β/miR-101/Lin28B Signaling Pathway." in: Integrative cancer therapies, Vol. 16, Issue 4, pp. 505-515, (2018) (PubMed).

Qin, Ke, Zhou, Wang, Liang, Wang, Yang, Gao, Ye, Kumar, Wang: "Metastasis-Associated Protein 1 Deficiency Results in Compromised Pulmonary Alveolar Capillary Angiogenesis in Mice." in: Medical science monitor : international medical journal of experimental and clinical research, Vol. 23, pp. 3932-3941, (2018) (PubMed).

Yang, Chen, Wang, Xian, Zhang, Zhu, Pan, Cheng: "TLR4 promotes the expression of HIF-1α by triggering reactive oxygen species in cervical cancer cells in vitro-implications for therapeutic intervention." in: Molecular medicine reports, Vol. 17, Issue 2, pp. 2229-2238, (2018) (PubMed).

Olcina, Balanis, Kim, Aksoy, Kodysh, Thompson, Hammerbacher, Graeber, Giaccia: "Mutations in an Innate Immunity Pathway Are Associated with Poor Overall Survival Outcomes and Hypoxic Signaling in Cancer." in: Cell reports, Vol. 25, Issue 13, pp. 3721-3732.e6, (2018) (PubMed).

Synonyme und alternative Namen zu ARNT

aryl hydrocarbon receptor nuclear translocator (ARNT), aryl hydrocarbon receptor nuclear translocator (Arnt), aryl hydrocarbon receptor nuclear translocator (arnt), aryl hydrocarbon receptor nuclear translocator S homeolog (arnt.S), ARNT, arnt.2, Arnt1, arnt1, bHLHe2, D3Ertd557e, Drnt, ESTM42, HIF-1-beta, HIF-1beta, hif-1beta, HIF1-beta, HIF1B, Hif1b, hif1b, HIF1BETA, hif1beta, MGC68805, mKIAA4051, TANGO, tango, W08714, xArnt, zgc:136664

Bezeichner auf Proteinebene für ARNT

  • class E basic helix-loop-helix protein 2
  • dioxin receptor, nuclear translocator
  • hypoxia-inducible factor 1, beta subunit
  • ARNT protein
  • HIF-1 beta
  • HIF-1-beta
  • HIF1-beta
  • aryl hydrocarbon receptor nuclear translocator
  • hypoxia-inducible factor 1 beta
  • hypoxia-inducible factor 1-beta
  • Aryl hydrocarbon receptor nuclear translocator 1
  • ARNT1
  • aryl hydrocarbon receptor nuclear translocater
  • aryl hydrocarbon receptor nuclear translocator 2
  • rtARNT
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