ATG4A Antikörper (AA 102-113) (FITC)

Produktnummer ABIN5065987

Produktdetails anti-ATG4A Antikörper (FITC)

Target: ATG4A (Autophagy related 4A Cysteine Peptidase (ATG4A))

Bindungsspezifität: AA 102-113

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ATG4A Antikörper ist konjugiert mit FITC

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)

Spezifität: Widely expressed, at a low level, and the highest expression is observed in skeletal muscle and brain. Also detected in fetal liver.,Detects ~45 kDa.

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Peptide Affinity Purified

Immunogen: Synthetic peptide from the mid-protein of Human ATG4A (aa. 102-113)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

• WB (1:1000)
• ICC/IF (1:100)
• optimal dilutions for assays should be determined by the user.

Kommentare:

A 1:1000 dilution of ABIN5065987 was sufficient for detection of ATG4A in 15 μg of Human HeLa Cell Lysates by ECL immunoblot analysis using goat anti-rabbit IgG:HRP as the secondary antibody.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.09 % sodium azide, Storage buffer may change when conjugated

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Conjugated antibodies should be stored at 4°C

Details zu ATG4A

Target: ATG4A (Autophagy related 4A Cysteine Peptidase (ATG4A))

Andere Bezeichnung: ATG4A (ATG4A Produkte)

Synonyme: apg4a antikoerper, autl2 antikoerper, F6E13.27 antikoerper, APG4A antikoerper, zgc:111958 antikoerper, Aut2a antikoerper, AUTL2 antikoerper, AI627006 antikoerper, AV169859 antikoerper, Apg4a antikoerper, Atg4al antikoerper, Autl2 antikoerper, Atg4a antikoerper, autophagy related 4A cysteine peptidase L homeolog antikoerper, autophagy related 4A cysteine peptidase antikoerper, Peptidase family C54 protein antikoerper, ATG4 autophagy related 4 homolog A (S. cerevisiae) antikoerper, autophagy related 4A, cysteine peptidase antikoerper, atg4a.L antikoerper, ATG4A antikoerper, AT2G44140 antikoerper, atg4a antikoerper, Atg4a antikoerper

Hintergrund: Autophagy related 4A, cysteine peptidase (ATG4A or APG4A) is a C-54 cysteine protease that also belongs to the family of autophagin proteins, and is primarily found in skeletal muscle and brain. ATG4A is involved in cellular autophagy and has been studied as a target for cancer therapy. Specifically it cleaves GATE-16. Mutations in the ATG4a gene is critical for redox regulation and inhibits autophagosome formation.

Gen-ID: 115201

NCBI Accession: NP_001308216

UniProt: Q8WYN0

Pathways: Autophagie