STAT2 Antikörper (pTyr690) (AbBy Fluor® 680)
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- Target Alle STAT2 Antikörper anzeigen
- STAT2 (Signal Transducer and Activator of Transcription 2, 113kDa (STAT2))
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Bindungsspezifität
- pTyr690
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Reaktivität
- Human, Ratte, Maus
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser STAT2 Antikörper ist konjugiert mit AbBy Fluor® 680
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Applikation
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Spezifität
- This phosphorylation site is homologous to that of Tyr689 in Mouse and Tyr690 in Rat.
- Kreuzreaktivität
- Human, Maus, Ratte
- Homologie
- Dog,Horse
- Aufreinigung
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic phosphopeptide derived from human Stat2 around the phosphorylation site of Tyr690
- Isotyp
- IgG
- Top Product
- Discover our top product STAT2 Primärantikörper
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- Applikationshinweise
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Haltbarkeit
- 12 months
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- Target
- STAT2 (Signal Transducer and Activator of Transcription 2, 113kDa (STAT2))
- Andere Bezeichnung
- Stat2 (STAT2 Produkte)
- Synonyme
- wu:fj84d07 antikoerper, p113 antikoerper, stat2 antikoerper, 1600010G07Rik antikoerper, AW496480 antikoerper, ISGF-3 antikoerper, P113 antikoerper, STAT113 antikoerper, signal transducer and activator of transcription 2 antikoerper, AGAP000099-PA antikoerper, stat2 antikoerper, STAT2 antikoerper, Stat2 antikoerper
- Hintergrund
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Synonyms: P113, ISGF-3, STAT113, Signal transducer and activator of transcription 2, STAT2
Background: Signal transducer and activator of transcription that mediates signaling by type I IFNs (IFN-alpha and IFN-beta). Following type I IFN binding to cell surface receptors, Jak kinases (TYK2 and JAK1) are activated, leading to tyrosine phosphorylation of STAT1 and STAT2. The phosphorylated STATs dimerize, associate with IRF9/ISGF3G to form a complex termed ISGF3 transcription factor, that enters the nucleus. ISGF3 binds to the IFN stimulated response element (ISRE) to activate the transcription of interferon stimulated genes, which drive the cell in an antiviral state.
- Gen-ID
- 6773
- UniProt
- P52630
- Pathways
- JAK-STAT Signalweg, Hepatitis C, CXCR4-mediated Signaling Events
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