TNFRSF10A Antikörper (N-Term)

Produktnummer ABIN499764

Produktdetails anti-TNFRSF10A Antikörper

Target: TNFRSF10A (Tumor Necrosis Factor Receptor Superfamily, Member 10a (TNFRSF10A))

Bindungsspezifität: N-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TNFRSF10A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Spezifität: DR4 antibody was raised against a peptide corresponding to amino acid 1 to 20 of human DR4 mature protein.

Aufreinigung: DEAE

Immunogen: Human DR4 (N-Terminus) Peptide

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA. Western Blot: 1/500 to 1/1000. A 57 kDa band can be detected. DR4 antibody has no crossreaction to DR5.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C.

Details zu TNFRSF10A

Target: TNFRSF10A (Tumor Necrosis Factor Receptor Superfamily, Member 10a (TNFRSF10A))

Andere Bezeichnung: CD261 / TRAILR1 (TNFRSF10A Produkte)

Synonyme: APO2 antikoerper, CD261 antikoerper, DR4 antikoerper, TRAILR-1 antikoerper, TRAILR1 antikoerper, TNFRSF10A antikoerper, TNF receptor superfamily member 10a antikoerper, tumor necrosis factor receptor superfamily member 26 antikoerper, tumor necrosis factor receptor superfamily, member 10a antikoerper, TNFRSF10A antikoerper, LOC510798 antikoerper

Hintergrund: Apoptosis, or programmed cell death, occurs during normal cellular differentiation and development of multicellular organisms. Apoptosis is induced by certain cytokines including TNF and Fas ligand in the TNF family through their death domain containing receptors, TNFR1 and Fas. A novel death domain containing receptor was recently identified and designated DR4 (for death receptor 4)1. The ligand for this novel death receptor has been identified and termed TRAIL2,3, which is a new member in the TNF family. DR4 is also called TRAIL receptor-1 (TRAIL-R1)4. DR4 is expressed in most of human tissues including spleen, peripheral blood leukocytes, small intestine and thymus. Like TNFR1, Fas and DR3, DR4 mediates apoptosis and NF-kappaB activation in many tissues and cells.Synonyms: APO2, DR4, Death receptor 4, TNF-related apoptosis-inducing ligand receptor 1, TNFRSF10A, TRAIL receptor 1, TRAIL-R1, Tumor necrosis factor receptor superfamily member 10A

Gen-ID: 8797

UniProt: O00220

Pathways: Apoptose, Positive Regulation of Endopeptidase Activity