TNFRSF10A Antikörper
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- Target Alle TNFRSF10A Antikörper anzeigen
- TNFRSF10A (Tumor Necrosis Factor Receptor Superfamily, Member 10a (TNFRSF10A))
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser TNFRSF10A Antikörper ist unkonjugiert
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Applikation
- Flow Cytometry (FACS), Immunohistochemistry (IHC)
- Spezifität
- Recognizes human TRAIL-R1.
- Kreuzreaktivität
- Human
- Kreuzreaktivität (Details)
- Does not cross-react with human TRAIL-R2, -R3 or -R4.
- Aufreinigung
- Purified from concentrated hybridoma tissue culture supernatant.
- Reinheit
- >95 % (SDS-PAGE)
- Immunogen
- Recombinant human TRAIL-R1 (DR4).
- Klon
- TR1-02
- Isotyp
- IgG2b
- Top Product
- Discover our top product TNFRSF10A Primärantikörper
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Kommentare
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Specially developed for the immunohistochemical detection of TRAIL-R1 in paraffin embedded tissue. Has been shown to detect TRAIL-R1 expressed at endogenous levels in paraffin-embedded tissue in different mammary carcinoma tissues.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- In PBS containing 10 % glycerol and 0.02 % sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
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Short Term Storage: +4°C
Long Term Storage: -20°C
Stable for at least 1 year after receipt when stored at -20°C. - Haltbarkeit
- 12 months
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- Target
- TNFRSF10A (Tumor Necrosis Factor Receptor Superfamily, Member 10a (TNFRSF10A))
- Andere Bezeichnung
- TRAIL-R1 (TNFRSF10A Produkte)
- Synonyme
- APO2 antikoerper, CD261 antikoerper, DR4 antikoerper, TRAILR-1 antikoerper, TRAILR1 antikoerper, TNFRSF10A antikoerper, TNF receptor superfamily member 10a antikoerper, tumor necrosis factor receptor superfamily member 26 antikoerper, tumor necrosis factor receptor superfamily, member 10a antikoerper, TNFRSF10A antikoerper, LOC510798 antikoerper
- Hintergrund
- TRAIL-R1 is a receptor for the cytotoxic ligand TRAIL. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Promotes the activation of NF-kappaB.
- UniProt
- O00220
- Pathways
- Apoptose, Positive Regulation of Endopeptidase Activity
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