RAD51 Antikörper

Produktnummer ABIN498997

Produktdetails anti-RAD51 Antikörper

Target: RAD51 (DNA Repair Protein Homolog 1 (RAD51))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RAD51 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Spezifität: This antibody detects endogenous levels of Rad51 protein. (region surrounding Thr309)

Kreuzreaktivität (Details): Species reactivity (tested):Human and Mouse.

Aufreinigung: Affinity chromatography

Reinheit: > 95 % by SDS-PAGE

Anwendungsinformationen

Applikationshinweise: Western Blot: 1/500 - 1/1000. Immunohistochemistry: 1/50 - 1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1,0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu RAD51

Target: RAD51 (DNA Repair Protein Homolog 1 (RAD51))

Andere Bezeichnung: RAD51 (RAD51 Produkte)

Synonyme: BRCC5 antikoerper, HRAD51 antikoerper, HsRad51 antikoerper, HsT16930 antikoerper, MRMV2 antikoerper, RAD51A antikoerper, RECA antikoerper, CRAD51 antikoerper, wu:fb38e12 antikoerper, zgc:77754 antikoerper, RGD1563603 antikoerper, ATRAD51 antikoerper, F22D1.20 antikoerper, F22D1_20 antikoerper, RAS associated with diabetes protein 51 antikoerper, AV304093 antikoerper, Rad51a antikoerper, Reca antikoerper, brcc5 antikoerper, rad51 antikoerper, rad51a antikoerper, reca antikoerper, xrad51 antikoerper, RAD51 recombinase antikoerper, RAS associated with diabetes protein 51 antikoerper, RAD51 recombinase L homeolog antikoerper, RAD51 antikoerper, rad51 antikoerper, Rad51 antikoerper, rad51.L antikoerper

Hintergrund: Rad51 is a recombinase that is essential for homologous recombination and double-strand break repair. It binds to single and double-stranded DNA, and has DNA-dependent ATPase activity. Rad51 unwinds duplex DNA and forms helical nucleoprotein filaments in a manner that is controlled through the action of DNA helicases that counteract nucleofilament formation. Rad51 interacts with BRCA1 and BRCA2, and also plays a role in p53-mediated signalling. Interaction of Rad51 with Chk1 kinase may occur in response to Chk1 phosphorylation.Synonyms: DNA repair protein RAD51 homolog 1, RAD51A, RECA

Molekulargewicht: approx. 42 kDa

Gen-ID: 5888

NCBI Accession: NP_002866

UniProt: Q06609

Pathways: DNA Reparatur