NME1 Antikörper
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- Target Alle NME1 Antikörper anzeigen
- NME1 (Non-Metastatic Cells 1, Protein (NM23A) Expressed in (NME1))
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser NME1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Spezifität
- This antibody detects endogenous levels of NM23-H1 protein. (region surrounding Tyr52)
- Kreuzreaktivität (Details)
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Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human. - Aufreinigung
- Affinity chromatography
- Reinheit
- > 95 % by SDS-PAGE
- Top Product
- Discover our top product NME1 Primärantikörper
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- Applikationshinweise
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Western Blot: 1/500 - 1/1000. Immunohistochemistry: 1/50 - 1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 1,0 mg/mL
- Buffer
- Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freezing and thawing.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Target
- NME1 (Non-Metastatic Cells 1, Protein (NM23A) Expressed in (NME1))
- Andere Bezeichnung
- NDP Kinase A (NME1 Produkte)
- Synonyme
- AWD antikoerper, GAAD antikoerper, NB antikoerper, NBS antikoerper, NDKA antikoerper, NDPK-A antikoerper, NDPKA antikoerper, NM23 antikoerper, NM23-H1 antikoerper, AL024257 antikoerper, NM23-M1 antikoerper, NM23A antikoerper, NDPK-Z1 antikoerper, NM23-B antikoerper, NM23-Z1 antikoerper, ndpkz1 antikoerper, nm23b antikoerper, nme1 antikoerper, nme2 antikoerper, nme2b1 antikoerper, NME1 antikoerper, NME1-NME2 antikoerper, NM23-C1 antikoerper, ndpk-b antikoerper, ndpkb antikoerper, nm23-h2 antikoerper, nm23ndk antikoerper, puf antikoerper, NBR-A antikoerper, NBR-B antikoerper, NME1-1 antikoerper, nm23ndk-a antikoerper, NDK I antikoerper, NDPK I antikoerper, T30A10.80 antikoerper, T30A10_80 antikoerper, NDP kinase I antikoerper, NME/NM23 nucleoside diphosphate kinase 1 antikoerper, NME/NM23 nucleoside diphosphate kinase 2b, tandem duplicate 1 antikoerper, non-metastatic cells 1, protein (NM23A) expressed in antikoerper, NME/NM23 nucleoside diphosphate kinase 2 S homeolog antikoerper, NME/NM23 nucleoside diphosphate kinase 2 L homeolog antikoerper, nucleoside diphosphate kinase antikoerper, nucleoside diphosphate kinase 1 antikoerper, NME1 antikoerper, Nme1 antikoerper, nme2b.1 antikoerper, nme2.S antikoerper, nme2.L antikoerper, LOC547870 antikoerper, NDPK1 antikoerper, LOC107790563 antikoerper
- Hintergrund
- The nm23 gene, a potential suppressor of metastasis, was originally identified by differential hybridization between two murine melanoma sub-lines, one with a high and the second with a low metastatic capacity. Highly metastatic sublines exhibit much lower levels of nm23 than less metastatic cells. Based on sequence analysis, nm23 appears highly related to nucleotide diphosphate kinases (NDP). In humans, NDP kinases A and B are identical to two isotypes of human nm23 homologs, namely nm23-H1 and -H2, respectively. nm23-H2 is identical in sequence to PuF, a transcription factor that binds to nucleasehypersensitive elements at positions 142 to 115 of the human c-Myc promotor.Synonyms: GAAD, Granzyme A-activated DNase, NDPKA, NM23, NME1, Nucleoside diphosphate kinase A, nm23-H1
- Molekulargewicht
- approx. 20 kDa
- Gen-ID
- 4830
- NCBI Accession
- NP_000260
- UniProt
- P15531
- Pathways
- Apoptose, Nucleotide Phosphorylation, Carbohydrate Homeostasis, Ribonucleoside Biosynthetic Process
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