GLUT1 Antikörper (AA 92-492)

Produktnummer ABIN4952587

Produktdetails anti-GLUT1 Antikörper

Target: GLUT1 (SLC2A1) (Solute Carrier Family 2 (Facilitated Glucose Transporter), Member 1 (SLC2A1))

Bindungsspezifität: AA 92-492

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GLUT1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Aufreinigung: Antigen affinity

Immunogen: Amino acids 92-492 of human SLC2A1 were used as the immunogen for the SLC2A1 antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the SLC2A1 antibody should be determined by the researcher.\. Western blot: 0.1-0.5 μg/mL,Immunocytochemistry: 0.5-1 μg/mL,IHC (Frozen): 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: -20 °C

Informationen zur Lagerung: After reconstitution, the SLC2A1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Details zu GLUT1

Target: GLUT1 (SLC2A1) (Solute Carrier Family 2 (Facilitated Glucose Transporter), Member 1 (SLC2A1))

Andere Bezeichnung: GLUT1 / SLC2A1 (SLC2A1 Produkte)

Synonyme: DYT17 antikoerper, DYT18 antikoerper, DYT9 antikoerper, EIG12 antikoerper, GLUT antikoerper, GLUT1 antikoerper, GLUT1DS antikoerper, HTLVR antikoerper, PED antikoerper, Glut-1 antikoerper, Glut1 antikoerper, GLUTB antikoerper, GTG1 antikoerper, Gtg3 antikoerper, RATGTG1 antikoerper, SLC2A1 antikoerper, GLT1 antikoerper, GLUCOSE TRANSPORTER 1 antikoerper, T21H19.70 antikoerper, T21H19_70 antikoerper, plastidic GLC translocator antikoerper, glut1 antikoerper, ped antikoerper, slc2a1 antikoerper, slc2a14 antikoerper, solute carrier family 2 member 1 antikoerper, solute carrier family 2 (facilitated glucose transporter), member 1 antikoerper, plastidic GLC translocator antikoerper, solute carrier family 2 (facilitated glucose transporter), member 1 L homeolog antikoerper, SLC2A1 antikoerper, Slc2a1 antikoerper, PGLCT antikoerper, slc2a1.L antikoerper

Hintergrund: GLUT1, also known as SLC2A1, is a major glucose transporter in the mammalian blood-brain barrier whose gene is mapped to 1p35-p31.3 and contains 10 exons. It is present at high levels in primate erythrocytes and brain endothelial cells. Not only can transport dehydroascorbic acid (the oxidized form of vitamin C) into the brain, GLUT1 is also likely to contribute to HTLV-associated disorders through interacting with HTLV envelope glycoproteins. Functionally, GLUT1 deficiency causes a decrease in embryonic glucose uptake and apoptosis, which may be involved in diabetic embryopathy, by contrast, an increased expression of GLUT1 in some malignant tumors may suggest a role for glucose-derivative tracers to detect in vivo thyroid cancer metastases by positron-emission tomography scanning.

UniProt: P11166

Pathways: Sensory Perception of Sound, Dicarboxylic Acid Transport, Warburg Effekt