CHRNA4 Antikörper (AA 29-43)

Produktnummer ABIN490506

Produktdetails anti-CHRNA4 Antikörper

Target: CHRNA4 (Cholinergic Receptor, Nicotinic, alpha 4 (CHRNA4))

Bindungsspezifität: AA 29-43

Reaktivität: Human, Ratte, Huhn, Affe

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser CHRNA4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Spezifität: Human CHRNA4. This antibody is expected NOT to cross-react with the similar alpha 2 subunit.

Homologie: Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Monkey, Marmoset, Elephant, Panda, Opossum, Turkey, Chicken, Lizard (100%) Bovine (93%) Mouse, Rat, Ferret, Hamster, Xenopus (87%).

Aufreinigung: Immunoaffinity purified

Immunogen: Synthetic peptide C-HVETRAHAEERLLKK from an internal region of human CHRNA4 (NP_000735.1). Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Monkey, Marmoset, Elephant, Panda, Opossum, Turkey, Chicken, Lizard (100%), Bovine (93%), Mouse, Rat, Ferret, Hamster, Xenopus (87%).

Type of Immunogen: Synthetic peptide

Anwendungsinformationen

Applikationshinweise: Approved: Peptide-ELISA (1:64000), WB (1 - 3 μg/mL)

Usage: Peptide ELISA: antibody detection limit dilution 1:64000. Western blot: Approx 70  kDa band observed in Rat Brain lysates (calculated MW of 70.0  kDa according to Human NP_000735.1and of 70.2  kDa according to Rat NP_077330.1). Recommended concentration: 1-3 μg/mL. An additional band of unknown identity was also consistently observed at 22  kDa. This band was successfully blocked by incubation with the immunising peptide.

Kommentare:

Target Species of Antibody: Human

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Tris-buffered saline,  pH 7.3, 0.5 % BSA, 0.02 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Minimize freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze-thaw cycles.

Details zu CHRNA4

Target: CHRNA4 (Cholinergic Receptor, Nicotinic, alpha 4 (CHRNA4))

Andere Bezeichnung: CHRNA4 / NACHR (CHRNA4 Produkte)

Synonyme: NACHRA4 antikoerper, BFNC antikoerper, EBN antikoerper, EBN1 antikoerper, NACHR antikoerper, NACRA4 antikoerper, NARAC antikoerper, Acra-4 antikoerper, Acra4 antikoerper, ENFL1 antikoerper, neuronal acetylcholine receptor subunit alpha-4 antikoerper, neuronal acetylcholine receptor subunit alpha-4-like antikoerper, cholinergic receptor nicotinic alpha 4 subunit antikoerper, cholinergic receptor, nicotinic, alpha 4b antikoerper, cholinergic receptor, nicotinic, alpha polypeptide 4 antikoerper, CpipJ_CPIJ002434 antikoerper, LOC100368057 antikoerper, CHRNA4 antikoerper, chrna4b antikoerper, Chrna4 antikoerper

Hintergrund: Name/Gene ID: CHRNA4
Subfamily: Nicotinic acetylcholine receptor
Family: Ion Channel

Synonyms: CHRNA4, BFNC, AChR-alpha4, Acra-4, EBN, EBN1, NACHR, NAChR alpha 4, NACRA4, NACHRA4, ENFL1

Gen-ID: 1137

NCBI Accession: NP_000735

UniProt: P43681

Pathways: Synaptic Membrane