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CHRNA4 Produkte

(Cholinergic Receptor, Nicotinic, alpha 4 (CHRNA4))

Kategorien

This gene encodes a nicotinic acetylcholine receptor, which belongs to a superfamily of ligand-gated ion channels that play a role in fast signal transmission at synapses. These pentameric receptors can bind acetylcholine, which causes an extensive change in conformation that leads to the opening of an ion-conducting channel across the plasma membrane. This protein is an integral membrane receptor subunit that can interact with either nAChR beta-2 or nAChR beta-4 to form a functional receptor. Mutations in this gene cause nocturnal frontal lobe epilepsy type 1. Polymorphisms in this gene that provide protection against nicotine addiction have been described. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2012].

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Ausgewählte CHRNA4 Kategorien

CHRNA4 Antikörper

High quality antibodies with extensive validation data.

CHRNA4 ELISA Kits

Reliable ELISA kits for a wide range of species.

CHRNA4 Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene CHRNA4 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation WB, ELISA, IHC (p), ICC, IHC (fro)
Validierungen
  • (5)
Kat. Nr. ABIN7444463
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, ELISA, IHC, ICC, FACS, Neut
Validierungen
  • (4)
Kat. Nr. ABIN5611309
Menge 0.1 mg
Datenblatt Datenblatt
Reaktivität Human, Mouse, Rat
Applikation WB, ELISA, IHC (p)
Validierungen
  • (3)
Kat. Nr. ABIN736746
Menge 100 μL
Datenblatt Datenblatt

Empfohlene CHRNA4 ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method
Validierungen
Kat. Nr. ABIN456521
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Mouse
Analytical Method
Validierungen
Kat. Nr. ABIN1144815
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Rat
Analytical Method
Validierungen
Kat. Nr. ABIN1144816
Menge 96 tests
Datenblatt Datenblatt

Empfohlene CHRNA4 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1349402
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
  • (1)
Kat. Nr. ABIN3087989
Menge 1 mg
Datenblatt Datenblatt
Reaktivität Human
Source Insect Cells
Validierungen
  • (1)
Kat. Nr. ABIN3087990
Menge 1 mg
Datenblatt Datenblatt

Neueste Publikationen zu unseren CHRNA4 Produkten

Chernyavsky, Shchepotin, Galitovkiy, Grando: "Mechanisms of tumor-promoting activities of nicotine in lung cancer: synergistic effects of cell membrane and mitochondrial nicotinic acetylcholine receptors." in: BMC cancer, Vol. 15, pp. 152, (2015) (PubMed).

Ishizuka, Ozawa, Goshima, Watanabe: "Involvement of nicotinic acetylcholine receptor in the proliferation of mouse induced pluripotent stem cells." in: Life sciences, Vol. 90, Issue 17-18, pp. 637-48, (2012) (PubMed).

Schwarz, Schwarz, Dorigo, Stützer, Wegner, Labarca, Deshpande, Gil, Berk, Lester: "Enhanced expression of hypersensitive alpha4* nAChR in adult mice increases the loss of midbrain dopaminergic neurons." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 20, Issue 7, pp. 935-46, (2006) (PubMed).

Bertrand, Picard, Le Hellard, Weiland, Favre, Phillips, Bertrand, Berkovic, Malafosse, Mulley: "How mutations in the nAChRs can cause ADNFLE epilepsy." in: Epilepsia, Vol. 43 Suppl 5, pp. 112-22, (2002) (PubMed).

Synonyme und alternative Namen zu CHRNA4

neuronal acetylcholine receptor subunit alpha-4 (CpipJ_CPIJ002434), neuronal acetylcholine receptor subunit alpha-4-like (LOC100368057), cholinergic receptor nicotinic alpha 4 subunit (CHRNA4), cholinergic receptor, nicotinic, alpha 4b (chrna4b), cholinergic receptor nicotinic alpha 4 subunit (Chrna4), cholinergic receptor, nicotinic, alpha polypeptide 4 (Chrna4), Acra-4, Acra4, BFNC, EBN, EBN1, ENFL1, NACHR, NACHRA4, NACRA4, NARAC

Bezeichner auf Proteinebene für CHRNA4

  • neuronal acetylcholine receptor subunit alpha-4
  • Neuronal acetylcholine receptor subunit alpha-4-like
  • cholinergic receptor, nicotinic, alpha 4
  • neuronal acetylcholine receptor subunit alpha-4-like
  • neuronal nicotinic acetylcholine receptor alpha 4 subunit
  • alpha-4 subunit, nicotinic acetylcholine receptor
  • cholinergic receptor, nicotinic, alpha polypeptide 4
  • neuronal nicotinic acetylcholine receptor alpha-4 subunit
  • Neuronal nicotinic acetylcholine receptor alpha 4 subunit
  • cholinergic receptor, nicotinic, alpha 4 subunit
  • neuronal acetylcholine receptor alpha-4 subunit
  • a4 nicotinic receptor
  • acetylcholine receptor alpha 4 neural
  • acetylcholine receptor, neuronal, nicotinic, alpha-4 subunit
  • alpha4 nAChR
  • alpha4-nAChR
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