CHRNA4 Antikörper (AA 29-242)

Produktnummer ABIN5611309

Produktdetails anti-CHRNA4 Antikörper

Target: CHRNA4 (Cholinergic Receptor, Nicotinic, alpha 4 (CHRNA4))

Bindungsspezifität: AA 29-242

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CHRNA4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC), Flow Cytometry (FACS), Neutralization (Neut)

Aufreinigung: purified

Immunogen: Purified recombinant fragment of human CHRNA4 (AA: extra 29-242) expressed in E. coli.

Klon: 7B4H1

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: ELISA: 1:10000, WB: 1:500 - 1:2000, ICC: N/A, FCM: N/A, IHC: N/A

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: 4°C, -20°C for long term storage

Details zu CHRNA4

Target: CHRNA4 (Cholinergic Receptor, Nicotinic, alpha 4 (CHRNA4))

Andere Bezeichnung: CHRNA4 (CHRNA4 Produkte)

Synonyme: NACHRA4 antikoerper, BFNC antikoerper, EBN antikoerper, EBN1 antikoerper, NACHR antikoerper, NACRA4 antikoerper, NARAC antikoerper, Acra-4 antikoerper, Acra4 antikoerper, ENFL1 antikoerper, neuronal acetylcholine receptor subunit alpha-4 antikoerper, neuronal acetylcholine receptor subunit alpha-4-like antikoerper, cholinergic receptor nicotinic alpha 4 subunit antikoerper, cholinergic receptor, nicotinic, alpha 4b antikoerper, cholinergic receptor, nicotinic, alpha polypeptide 4 antikoerper, CpipJ_CPIJ002434 antikoerper, LOC100368057 antikoerper, CHRNA4 antikoerper, chrna4b antikoerper, Chrna4 antikoerper

Hintergrund:

Description: This gene encodes a nicotinic acetylcholine receptor, which belongs to a superfamily of ligand-gated ion channels that play a role in fast signal transmission at synapses. These pentameric receptors can bind acetylcholine, which causes an extensive change in conformation that leads to the opening of an ion-conducting channel across the plasma membrane. This protein is an integral membrane receptor subunit that can interact with either nAChR beta-2 or nAChR beta-4 to form a functional receptor. Mutations in this gene cause nocturnal frontal lobe epilepsy type 1. Polymorphisms in this gene that provide protection against nicotine addiction have been described. Alternative splicing results in multiple transcript variants.

Aliases: EBN, BFNC, EBN1, NACHR, NACRA4, NACHRA4

Molekulargewicht: 70 kDa

Gen-ID: 1137

HGNC: 1137

Pathways: Synaptic Membrane