Leptin Antikörper
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- Target Alle Leptin (LEP) Antikörper anzeigen
- Leptin (LEP)
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Reaktivität
- Human, Maus
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser Leptin Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (IHC)
- Produktmerkmale
- Leptin is a 16 kDa adipocyte-derived hormone that relays the status of the body's energy reserves to the hypothalamus, resulting in the suppression of appetite and modulation of energy expenditure (1,2). Leptin functions as a pleiotropic cytokine with multiple roles in immune function and reproduction (1-4). There are at least five isoforms of the leptin receptor, but only OB-Rb is signaling competent (1,2). OB-Rb is expressed on a number of cells, including T cells, B cells, keratinocytes, and others (1-6). Leptin/OB-Rb interactions induce Jak2, PI3K, Erk1/2, and Stat3 activation (1,2). OB-Rb is often highly expressed in many tumor types, including breast, pancreatic, and Tumor Initiating Stem Cells (TISCS), providing a potential mechanistic link for the tumor promoting effects of obesity (2,7).
- Aufreinigung
- Affinity purification
- Immunogen
- Recombinant protein of human LEP.
- Isotyp
- IgG
- Top Product
- Discover our top product LEP Primärantikörper
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anti-Leptin (LEP) (AA 22-167) antibody
LEP Reaktivität: Human WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Leptin (LEP) (AA 22-167) antibodyLEP Reaktivität: Ratte WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Leptin (LEP) (AA 17-100) antibodyLEP Reaktivität: Human, Maus, Ratte WB, ELISA, IF (p), IF (cc), IHC (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-Leptin (LEP) (AA 8-37) antibodyLEP Reaktivität: Human WB, ELISA, IHC, IF, FACS Wirt: Kaninchen Polyclonal unconjugated
anti-Leptin (LEP) (AA 22-167) antibodyLEP Reaktivität: Maus WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Leptin (LEP) (AA 29-160) antibodyLEP Reaktivität: Rind (Kuh) WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Leptin (LEP) antibodyLEP Reaktivität: Human, Maus, Ratte IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Leptin (LEP) (AA 22-167) antibodyLEP Reaktivität: Human WB, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Leptin (LEP) (AA 7-37), (N-Term) antibodyLEP Reaktivität: Human WB, IF, FACS, EIA, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-Leptin (LEP) (AA 22-167) antibodyLEP Reaktivität: Human WB, IHC, IP, ICC Wirt: Maus Monoclonal C5 unconjugated
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- Applikationshinweise
- WB 1:200-1:500 , IHC 1:50-1:100
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.4
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze/thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C.
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- Target
- Leptin (LEP)
- Andere Bezeichnung
- LEP (LEP Produkte)
- Synonyme
- ob antikoerper, obese antikoerper, LEPD antikoerper, OB antikoerper, OBS antikoerper, leptin antikoerper, Lep antikoerper, LEP antikoerper, lep antikoerper
- Gen-ID
- 3952
- UniProt
- P41159
- Pathways
- JAK-STAT Signalweg, AMPK Signaling, Hormone Transport, Peptide Hormone Metabolism, Hormone Activity, Negative Regulation of Hormone Secretion, Regulation of Carbohydrate Metabolic Process, Feeding Behaviour, Monocarboxylic Acid Catabolic Process
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