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Insulin Receptor Antikörper (AA 811-860)

INSR Reaktivität: Human WB, ELISA Wirt: Kaninchen Polyclonal unconjugated

Produktnummer ABIN5610485

Datenblatt (PDF)

Target Alle Insulin Receptor (INSR) Antikörper anzeigen

Insulin Receptor (INSR)
Bindungsspezifität
16

15

13

12

9

8

8

7

6

6

5

5

5

4

4

4

4

3

3

3

2

2

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 811-860
Reaktivität
172

97

82

16

14

9

8

7

6

5

4

3

2

2

1

1

1

1

1

1

1
Human
Wirt
166

27

3

1
Kaninchen
Passende Sekundärantikörper
Klonalität
158

39
Polyklonal
Konjugat
121

16

16

7

7

5

3

3

3

3

3

3

1

1

1

1

1

1

1
Dieser Insulin Receptor Antikörper ist unkonjugiert
Applikation
142

82

52

29

18

16

16

15

13

13

8

5

4

4

4

2

1

1

1

1

1

1
Western Blotting (WB), ELISA

Verwendungszweck

Rabbit polyclonal to Insulin R.

Spezifität

The antibody detects endogenous Insulin R .

Produktmerkmale

Rabbit Polyclonal to Insulin R.

Aufreinigung

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen

Synthetic peptide from human Insulin R protein.

Isotyp

IgG

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INSR Reaktivität: Human, Maus WB, IHC (p) Wirt: Kaninchen Polyclonal RB1421 unconjugated

Applikationshinweise

WB 1:500-2000
ELISA 1:10000-20000

Kommentare

Isoform Long and isoform Short are predominantly expressed in tissue targets of insulin metabolic effects: liver, adipose tissue and skeletal muscle but are also expressed in the peripheral nerve, kidney, pulmonary alveoli, pancreatic acini, placenta vascular endothelium, fibroblasts, monocytes, granulocytes, erythrocytes and skin. Isoform Short is preferentially expressed in fetal cells such as fetal fibroblasts, muscle, liver and kidney. Found as a hybrid receptor with IGF1R in muscle, heart, kidney, adipose tissue, skeletal muscle, hepatoma, fibroblasts, spleen and placenta (at protein level). Overexpressed in several tumors, including breast, colon, lung, ovary, and thyroid carcinomas.

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Konzentration

1 mg/mL

Buffer

Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel

Sodium azide

Vorsichtsmaßnahmen

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung

Avoid repeated freeze/thaw cycles.

Lagerung

-20 °C

Informationen zur Lagerung

Store at -20°C, and avoid repeat freeze-thaw cycles.
Target

Insulin Receptor (INSR)

Andere Bezeichnung

Insulin R (INSR Produkte)

Synonyme

CD220 antikoerper, HHF5 antikoerper, 4932439J01Rik antikoerper, D630014A15Rik antikoerper, IR antikoerper, IR-A antikoerper, IR-B antikoerper, 18402 antikoerper, CG18402 antikoerper, DIHR antikoerper, DILR antikoerper, DIR antikoerper, DIRH antikoerper, DIRbeta antikoerper, DInR antikoerper, DInr antikoerper, Dir-a antikoerper, Dir-b antikoerper, Dmel\\CG18402 antikoerper, INR antikoerper, INS antikoerper, Inr antikoerper, Inr-alpha antikoerper, Inr-beta antikoerper, InsR antikoerper, dINR antikoerper, dIR antikoerper, dIRH antikoerper, dInR antikoerper, dInr antikoerper, dInsR antikoerper, dinr antikoerper, dir antikoerper, er10 antikoerper, inr antikoerper, insulin/insulin-like growth factor receptor antikoerper, l(3)05545 antikoerper, l(3)93Dj antikoerper, l(3)er10 antikoerper, lnR antikoerper, ir-A antikoerper, CTK-1 antikoerper, ir antikoerper, INSR antikoerper, NV14476 antikoerper, cd220 antikoerper, hhf5 antikoerper, insulin receptor antikoerper, Insulin-like receptor antikoerper, insulin receptor L homeolog antikoerper, INSR antikoerper, Insr antikoerper, InR antikoerper, LOC100122567 antikoerper, LOC100451802 antikoerper, insr.L antikoerper

Gen-ID

3643

UniProt

P06213

Pathways

NF-kappaB Signalweg, RTK Signalweg, AMPK Signaling, Carbohydrate Homeostasis, Regulation of Cell Size, Regulation of Carbohydrate Metabolic Process, Growth Factor Binding, Negative Regulation of Transporter Activity