ATF4 Antikörper (N-Term)
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- Target Alle ATF4 Antikörper anzeigen
- ATF4 (Activating Transcription Factor 4 (Tax-Responsive Enhancer Element B67) (ATF4))
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Bindungsspezifität
- AA 71-100, N-Term
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser ATF4 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Verwendungszweck
- Rabbit IgG polyclonal antibody for Cyclic AMP-dependent transcription factor ATF-4(ATF4) detection. Tested with WB in Human.
- Sequenz
- SNNSKEDAFS GTDWMLEKMD LKEFDLDALL
- Kreuzreaktivität (Details)
- No cross reactivity with other proteins.
- Produktmerkmale
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Rabbit IgG polyclonal antibody for Cyclic AMP-dependent transcription factor ATF-4(ATF4) detection. Tested with WB in Human.
Gene Name: activating transcription factor 4 (tax-responsive enhancer element B67)
Protein Name: Cyclic AMP-dependent transcription factor ATF-4 - Aufreinigung
- Immunogen affinity purified.
- Immunogen
- A synthetic peptide corresponding to a sequence at the N-terminus of human ATF4 (71-100aa SNNSKEDAFSGTDWMLEKMDLKEFDLDALL), different from the related mouse and rat sequences by five amino acids.
- Isotyp
- IgG
- Top Product
- Discover our top product ATF4 Primärantikörper
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- Applikationshinweise
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WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human
Notes: Tested Species: Species with positive results.
Other applications have not been tested. Optimal dilutions should be determined by end users. - Kommentare
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- Konzentration
- 500 μg/mL
- Buffer
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freezing and thawing.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
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At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
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MARVELD1 Inhibits Nonsense-Mediated RNA Decay by Repressing Serine Phosphorylation of UPF1." in: PLoS ONE, Vol. 8, Issue 6, pp. e68291, (2013) (PubMed).
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MARVELD1 Inhibits Nonsense-Mediated RNA Decay by Repressing Serine Phosphorylation of UPF1." in: PLoS ONE, Vol. 8, Issue 6, pp. e68291, (2013) (PubMed).
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- Target
- ATF4 (Activating Transcription Factor 4 (Tax-Responsive Enhancer Element B67) (ATF4))
- Andere Bezeichnung
- ATF4 (ATF4 Produkte)
- Synonyme
- CREB-2 antikoerper, CREB2 antikoerper, TAXREB67 antikoerper, TXREB antikoerper, ATF4 antikoerper, atf-4 antikoerper, creb-2 antikoerper, creb2 antikoerper, taxreb67 antikoerper, txreb antikoerper, atf4 antikoerper, wu:fj01c08 antikoerper, wu:fk30b04 antikoerper, zgc:85951 antikoerper, sb:eu681 antikoerper, wu:fb08f07 antikoerper, zgc:171702 antikoerper, Atf-4 antikoerper, C/ATF antikoerper, ATF4-I antikoerper, atf4-a antikoerper, atf4-b antikoerper, atf4-ii antikoerper, activating transcription factor 4 antikoerper, activating transcription factor 4 L homeolog antikoerper, activating transcription factor 4a antikoerper, activating transcription factor 4b antikoerper, activating transcription factor 4 S homeolog antikoerper, ATF4 antikoerper, atf4 antikoerper, Atf4 antikoerper, atf4.L antikoerper, atf4a antikoerper, atf4b antikoerper, atf4.S antikoerper
- Hintergrund
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ATF4, Activating Transcription Factor 4, is also known as CREB2. ATF4 belongs to the large ATF/CREB family of transcription factors which bind DNA via their basic region and dimerize via their leucine zipper domain to form a variety of homo- and heterodimers to regulate gene transcription. It is identified that members of this family share significant sequence similarity within a leucine zipper DNA-binding motif and an adjacent basic region. The ATF4 gene is mapped to chromosome 22. Unlike CREB, which activates transcription from CRE-containing promoters, CREB2 functions as a specific repressor of CRE-dependent transcription. The transcriptional repressor activity resides within the C-terminal leucine zipper and basic domain region of the CREB2 protein.
Synonyms: ATF 4 | ATF4 protein | DNA-binding protein TAXREB67 | TaxREB67 | TXREB | P18848 - Gen-ID
- 468
- UniProt
- P18848
- Pathways
- Thyroid Hormone Synthesis, Myometrial Relaxation and Contraction, ER-Nucleus Signaling, Unfolded Protein Response
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