ATF4 Antikörper (N-Term)

Produktnummer ABIN2780377

Zitiert in 1 Publikation. Der Kaninchen Polyklonal anti-ATF4 Antikörper (ABIN2780377) detektiert spezifisch ATF4 in WB und IHC (p). Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus, Ratte, Hund, Rind (Kuh), Meerschweinchen und Schaf.

Kurzübersicht für ATF4 Antikörper (N-Term) (ABIN2780377)

Target: ATF4 (Activating Transcription Factor 4 (Tax-Responsive Enhancer Element B67) (ATF4))

Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Meerschweinchen, Schaf

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ATF4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-ATF4 Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: Atf4 Antibody - N-terminal region

Sequenz: VLAGDLMSPF DQSGLGAEES LGLLDDYLEV AKHLKPHGFS SDKAGSSEWP

Homologie: Cow: 86%, Dog: 100%, Guinea Pig: 93%, Human: 100%, Mouse: 92%, Rat: 100%, Sheep: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against Atf4. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide corresponding to a region of Mouse

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP38066-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-ATF4 Antikörper (ABIN2780377)

Kalinec, Thein, Parsa, Yorgason, Luxford, Urrutia, Kalinec: "Acetaminophen and NAPQI are toxic to auditory cells via oxidative and endoplasmic reticulum stress-dependent pathways." in: Hearing research, Vol. 313, pp. 26-37, (2014) (PubMed).

Details zu ATF4

Target: ATF4 (Activating Transcription Factor 4 (Tax-Responsive Enhancer Element B67) (ATF4))

Andere Bezeichnung: Atf4

Hintergrund:

Background Information: The function of Atf4 remains unknown.

Gene Name: Activating transcription factor 4

Alternative Symbols: Atf-, C/AT, CREB, Atf-4, C/ATF, CREB2, CREB-2, TAXREB, TAXREB67

Protein Name: Cyclic AMP-dependent transcription factor ATF-4

Molekulargewicht: 38kDa

Gen-ID: 11911

NCBI Accession: NP_033846

UniProt: Q5U4B2

Pathways: Thyroid Hormone Synthesis, Myometrial Relaxation and Contraction, ER-Nucleus Signaling, Unfolded Protein Response