AGT Antikörper (N-Term)

Produktnummer ABIN4886440

Produktdetails anti-AGT Antikörper

Target: AGT (Angiotensinogen (serpin Peptidase Inhibitor, Clade A, Member 8) (AGT))

Bindungsspezifität: AA 25-36, N-Term

Reaktivität: Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser AGT Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Verwendungszweck: Rabbit IgG polyclonal antibody for Angiotensinogen(AGT) detection. Tested with WB in Mouse,Rat.

Sequenz: DRVYIHPFHL LY

Kreuzreaktivität (Details): No cross reactivity with other proteins.

Produktmerkmale: Rabbit IgG polyclonal antibody for Angiotensinogen(AGT) detection. Tested with WB in Mouse,Rat.
Gene Name: angiotensinogen(serpin peptidase inhibitor, clade A, member 8)
Protein Name: Angiotensinogen

Aufreinigung: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of mouse Angiotensinogen(25-36aa DRVYIHPFHLLY), identical to the related rat sequence.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Mouse, Rat
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Kommentare:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Konservierungsmittel: Sodium azide, Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Referenzen für anti-AGT Antikörper (ABIN4886440)

Lan, Yue, Han, Shi, Yang, Pu, Yao, Kang: "Genome-wide identification of TCF7L2/TCF4 target miRNAs reveals a role for miR-21 in Wnt-driven epithelial cancer." in: International journal of oncology, Vol. 40, Issue 2, pp. 519-26, (2011) (PubMed).

Details zu AGT

Target: AGT (Angiotensinogen (serpin Peptidase Inhibitor, Clade A, Member 8) (AGT))

Andere Bezeichnung: AGT (AGT Produkte)

Synonyme: ANHU antikoerper, SERPINA8 antikoerper, AI265500 antikoerper, AngI antikoerper, AngII antikoerper, Aogen antikoerper, Serpina8 antikoerper, ANRT antikoerper, Ang antikoerper, PAT antikoerper, wu:fb62f06 antikoerper, wu:fj87b02 antikoerper, zgc:111892 antikoerper, AGT antikoerper, angt antikoerper, ANGT antikoerper, angiotensinogen antikoerper, angiotensinogen (serpin peptidase inhibitor, clade A, member 8) antikoerper, AGT antikoerper, Agt antikoerper, agt antikoerper

Hintergrund: AGT(ANGIOTENSINOGEN), also called SERPINA8, is an alpha-2-globulin that is produced constitutively and released into the circulation mainly by the liver. ATG is a member of the serpin family, although it is not known to inhibit other enzymes, unlike most serpins. Angiotensinogen is also known as renin substrate. The AGT gene is mapped on 1q42.2. And the human angiotensinogen gene contains 5 exons. The expression of AGT and enzymes required for its conversion to angiotensin II in human adipose tissue. Western blot analysis showed a distinct band of expected size of the angiotensinogen protein(61 kD) in isolated adipocytes. The more pronounced AGT increase in TT subjects resulted in similar plasma renin activity at a lower plasma active renin concentration, with a higher plasma renin activity/active renin ratio.

Synonyms: Aangiotensinogen(serpin peptidase inhibitor clade A member 8) antibody|AGT antibody|AI265500 antibody|Alpha 1 antiproteinase antitrypsin antibody|Ang antibody|Ang I antibody|Ang II antibody|Ang III antibody|AngII antibody|Angiotensin I antibody|Angiotensin II antibody|Angiotensin III antibody|Angiotensin-3 antibody|Angiotensinogen(PAT) antibody|Angiotensinogen antibody|ANGT_HUMAN antibody|ANHU antibody|ANRT antibody|Des-Asp-angiotensin II antibody|FLJ92595 antibody|FLJ97926 antibody|MGC105326 antibody|PAT antibody|Pre angiotensinogen antibody|Serine(or cysteine) proteinase inhibitor antibody|Serpin A8 antibody|Serpin peptidase inhibitor clade A member 8 antibody|SERPINA8 antibody

UniProt: P11859

Pathways: JAK-STAT Signalweg, ACE Inhibitor Pathway, EGFR Signaling Pathway, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Regulation of Lipid Metabolism by PPARalpha, Protein targeting to Nucleus, Feeding Behaviour, Monocarboxylic Acid Catabolic Process, Dicarboxylic Acid Transport, Positive Regulation of Response to DNA Damage Stimulus, Regulation of long-term Neuronal Synaptic Plasticity