Lysine (K)-Specific Methyltransferase 2B (KMT2B) (AA 2703-2715) Antikörper

Produktnummer ABIN462281

Produktdetails

Target: Lysine (K)-Specific Methyltransferase 2B (KMT2B)

Bindungsspezifität: AA 2703-2715

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Affe, Schwein, Zebrafisch (Danio rerio)

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Marke: IHC-plus™

Spezifität: Human MLL4.

Homologie: Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Mouse, Rat, Bovine, Pig, Zebrafish (100%) Xenopus, Pufferfish (92%) Chimpanzee, Elephant, Panda, Dog, Bat, Horse, Opossum, Turkey, Chicken (85%).

Aufreinigung: Immunoaffinity purified

Immunogen: Synthetic peptide CNCGAKRCRRFLN from the C-terminus of human MLL4 (NP_055542.1). Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Mouse, Rat, Bovine, Pig, Zebrafish (100%), Xenopus, Pufferfish (92%), Chimpanzee, Elephant, Panda, Dog, Bat, Horse, Opossum, Turkey, Chicken (85%).

Type of Immunogen: Synthetic peptide

Anwendungsinformationen

Applikationshinweise: Approved: IHC, IHC-P (5 μg/mL), Peptide-ELISA (1:128000)

Usage: Immunohistochemistry: This antibody was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in  pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for this antibody was determined to be 5 μg/mL.

Kommentare:

Target Species of Antibody: Human

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Tris-buffered saline,  pH 7.3, 0.5 % BSA, 0.02 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Minimize freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze-thaw cycles.

Antigendetails

Target: Lysine (K)-Specific Methyltransferase 2B (KMT2B)

Andere Bezeichnung: KMT2B / MLL4 (KMT2B Produkte)

Synonyme: HRX2 antikoerper, MLL1B antikoerper, MLL2 antikoerper, MLL4 antikoerper, TRX2 antikoerper, WBP7 antikoerper, lysine methyltransferase 2B antikoerper, KMT2B antikoerper

Hintergrund: Name/Gene ID: KMT2B

Synonyms: KMT2B, Lysine N-methyltransferase 2D, MLL4, HRX2, KMT2D, WBP-7, WW domain binding protein 7, Trithorax homologue 2, WBP7, KIAA0304, Lysine N-methyltransferase 2B, Trithorax homolog 2, TRX2, WW domain-binding protein 7

Gen-ID: 9757

NCBI Accession: NP_055542

UniProt: Q9UMN6

Pathways: Warburg Effekt