Lysine (K)-Specific Methyltransferase 2B (KMT2B) (AA 445-599) Antikörper

Produktnummer ABIN7193438

Produktdetails

Target: Lysine (K)-Specific Methyltransferase 2B (KMT2B)

Bindungsspezifität: AA 445-599

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC), Western Blotting (WB), Flow Cytometry (FACS)

Aufreinigung: purified

Immunogen: Purified recombinant fragment of human KMT2D (AA: 445-599) expressed in E. coli.

Klon: 1D10F6

Isotyp: IgG2b

Anwendungsinformationen

Applikationshinweise: WB:1:500 - 1:2000, IHC:1:200 - 1:1000, FCM:1:200 - 1:400, ELISA:1:10000,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: Purified antibody in PBS with 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: 4°C, -20°C for long term storage

Antigendetails

Target: Lysine (K)-Specific Methyltransferase 2B (KMT2B)

Andere Bezeichnung: KMT2D (KMT2B Produkte)

Synonyme: HRX2 antikoerper, MLL1B antikoerper, MLL2 antikoerper, MLL4 antikoerper, TRX2 antikoerper, WBP7 antikoerper, lysine methyltransferase 2B antikoerper, KMT2B antikoerper

Hintergrund:

Description: The protein encoded by this gene is a histone methyltransferase that methylates the Lys-4 position of histone H3. The encoded protein is part of a large protein complex called ASCOM, which has been shown to be a transcriptional regulator of the beta-globin and estrogen receptor genes. Mutations in this gene have been shown to be a cause of Kabuki syndrome.

Aliases: ALR, KMS, MLL2, MLL4, AAD10, KABUK1, TNRC21, CAGL114

Molekulargewicht: 593 kDa

Gen-ID: 8085

Pathways: Warburg Effekt