CBFB Antikörper (Middle Region)

Produktnummer ABIN452819

Produktdetails anti-CBFB Antikörper

Target: CBFB (Core-Binding Factor, beta Subunit (CBFB))

Bindungsspezifität: Middle Region

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CBFB Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Spezifität: This antibody detects CBFB at Center.

Kreuzreaktivität (Details): Species reactivity (tested):Human

Aufreinigung: Purified through a protein A column, followed by peptide affinity purification

Immunogen: KLH conjugated synthetic peptide selected from the Center region of human CBFB

Anwendungsinformationen

Applikationshinweise: Western blot: 1: 100 - 1: 500.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.

Details zu CBFB

Target: CBFB (Core-Binding Factor, beta Subunit (CBFB))

Andere Bezeichnung: CBFB (CBFB Produkte)

Synonyme: PEBP2B antikoerper, Cbfb antikoerper, pebp2b antikoerper, Pebp2 antikoerper, CBFB antikoerper, unp1266 antikoerper, cbf-beta antikoerper, cbfbeta antikoerper, pea2-beta antikoerper, pebp2-beta antikoerper, AI893578 antikoerper, PEA2 antikoerper, PEBP2b antikoerper, Pebpb2 antikoerper, core-binding factor beta subunit antikoerper, core binding factor beta subunit antikoerper, core-binding factor, beta subunit antikoerper, core-binding factor, beta subunit S homeolog antikoerper, core binding factor beta antikoerper, CBFB antikoerper, Cbfb antikoerper, cbfb antikoerper, cbfb.S antikoerper

Hintergrund: CBFB is the beta subunit of a heterodimeric core-binding transcription factor belonging to the PEBP2/CBF transcription factor family which master-regulates a host of genes specific to hematopoiesis (e.g., RUNX1) and osteogenesis (e.g., RUNX2). The beta subunit is a non-DNA binding regulatory subunit, it allosterically enhances DNA binding by alpha subunit as the complex binds to the core site of various enhancers and promoters, including murine leukemia virus, polyomavirus enhancer, T-cell receptor enhancers and GM-CSF promoters.Synonyms: CBF beta, CBF-beta, Core-binding factor beta, PEA2-beta, PEBP2-beta, Polyomavirus enhancer-binding protein 2 beta subunit, SL3-3 enhancer factor 1 subunit beta, SL3/AKV core-binding factor beta subunit

Molekulargewicht: 21508 Da

Gen-ID: 865

NCBI Accession: NP_001746

UniProt: Q13951

Pathways: Regulation of Lipid Metabolism by PPARalpha